Why Is TEMPUS AI INC A (TEM) Stock Up Today?

Tempus AI shares surged 13.55% to close at $82.01, driven by third-quarter results that exceeded expectations and a raised full-year revenue outlook. The stock also benefited from a price target increase by Needham and the completion of regulatory review for its pending acquisition of Personalis.

What Happened

Tempus AI reported third-quarter revenue of $411.5 million, a 23% year-over-year increase, which surpassed analyst estimates. The company posted an adjusted EPS of $0.07 against a consensus estimate of a loss of $0.08. Management raised its full-year 2026 revenue guidance to $1.605 billion. Oncology volume grew 32%, and data licensing bookings reached over $550 million year-to-date. Gross margin expanded to 64.8% from 62.8% in the prior year period. Needham raised its price target to $89 and maintained a Buy rating, citing data growth. The company also cleared regulatory review for its acquisition of Personalis, with a shareholder vote scheduled for November 30. Cathie Wood’s ARK Invest purchased over 154,000 shares ahead of the earnings release.

What The Data Shows

The stock opened at $74.40, a 3.0% gap up from the prior close of $72.22. It reached a session high of $82.10 at 12:55 PM ET and a low of $70.30 at 9:30 AM ET. Trading volume reached 7.6 million shares, which is 1.2 times the three-month daily average. Over the last eight sessions, the stock had already gained 6.6% before this move. The company has a market capitalization of $13.0 billion and remains unprofitable with a trailing twelve-month EPS of -$1.43. Revenue growth over the trailing twelve months stands at 50.4%. The stock has printed 27 fresh 52-week highs and 3 fresh 52-week lows on November 2, 2026. Recent insider activity includes 25 sales totaling $91.6 million in the last 90 days, with no buys. Eric P. Lefkofsky, the CEO, sold shares on October 27, 2026.

What To Watch

Investors will monitor the shareholder vote on the Personalis acquisition scheduled for November 30. The company’s ability to sustain its raised revenue guidance and improve net margins will be key metrics for future performance.