TOP TIERMARKET NEWSWIRE
Movers explained · 2026-08-21

Archived explainer. For the current picture see today's TEM page.

Why Is TEMPUS AI INC A (TEM) Stock Up Today?

By the Top Tier Newswire AI Desk · August 21, 2026 at 12:05 AM ET · reviewed against 11 wire stories

TEMPUS AI INC A (TEM) is up +8.82% in the latest session. Our newswire has captured 11 stories on TEM across 5 sources in the last 36 hours, with AI sentiment reading bullish (avg 67/100).

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Tempus AI Inc A stock rose 8.82% to $66.65 on Thursday, marking one of its largest intraday gains in recent months. The move followed a price target increase from BTIG analyst Mark Massaro and broader market enthusiasm for advances in oncology and mRNA technologies. The stock is also benefiting from a growing narrative around the validation of its business model through recent developments in the sector.

What Happened

BTIG analyst Mark Massaro raised the price target on Tempus AI to $80 from $70 and maintained a Buy rating. This upgrade came after a broader market rally in oncology and biotech stocks, driven by Moderna’s 177% surge following a major breakthrough in its cancer vaccine trial. The momentum extended to other mRNA-related names, including Merck, BioNTech, and Tempus AI. Tempus AI also recently completed a strategic acquisition of Personalis, which analysts say reinforces its position in the oncology space. The stock’s upward trajectory reflects both the sector’s optimism and the firm’s own strategic progress.

What The Data Shows

Tempus AI’s stock has been volatile over the past 52 weeks, trading between $40.77 and $104.32. The recent intraday move pushed the stock to a fresh 52-week high on August 21. The stock has also seen unusual options activity in the last 36 hours, with $29.1 million in call premiums compared to just $44,000 in puts. The largest single options print totaled $6.3 million. Meanwhile, insider selling has continued, with 18 transactions totaling $47.5 million recorded in the last 90 days. No insider purchases have been reported during that period.

What To Watch

The stock is currently on track for its best week in four months. Investors should continue to monitor the broader oncology and biotech sectors for further catalysts. Coverage of Tempus AI has increased significantly in the last 36 hours, with 11 stories from five sources. The next major event for the company will be its scheduled earnings release, if one is announced.

AI-assisted analysis composed exclusively from headlines and data on the Top Tier newswire. Public view is delayed 4 hours from real time. Not financial advice.

TEM by the numbers

Last: $66.65Session: +8.82%7 sessions: +33.11%Coverage: 11 stories / 5 sourcesAI sentiment: 67/100 (bullish)Mkt cap: $8.9B52w: $40.77 to $104.32
TEM · Aug 21 session (5-min) · +8.06% vs prior close · updated 8:51 PM ET
$64.21$68.77$73.33prev close $66.65$72.027:00 AM10:13 AM1:27 PM4:41 PM7:55 PM7:00 AM · $64.707:05 AM · $64.837:10 AM · $64.807:15 AM · $64.757:20 AM · $65.007:25 AM · $65.017:30 AM · $65.067:35 AM · $64.857:40 AM · $64.817:45 AM · $64.757:50 AM · $64.827:55 AM · $64.958:00 AM · $64.958:05 AM · $65.348:10 AM · $65.038:15 AM · $65.368:20 AM · $65.208:25 AM · $65.028:30 AM · $65.188:35 AM · $65.178:40 AM · $65.298:45 AM · $65.298:50 AM · $65.268:55 AM · $65.359:00 AM · $65.339:05 AM · $65.419:10 AM · $65.299:15 AM · $65.209:20 AM · $65.239:25 AM · $65.789:30 AM · $65.639:35 AM · $66.289:40 AM · $66.329:45 AM · $66.789:50 AM · $67.759:55 AM · $67.3610:00 AM · $68.5410:05 AM · $68.2710:10 AM · $68.5010:15 AM · $68.0510:20 AM · $68.6510:25 AM · $68.2110:30 AM · $68.7210:35 AM · $69.1710:40 AM · $69.1510:45 AM · $70.4510:50 AM · $69.9310:55 AM · $70.1111:00 AM · $70.6411:05 AM · $69.4111:10 AM · $69.3911:15 AM · $68.8211:20 AM · $69.0011:25 AM · $69.5411:30 AM · $69.6911:35 AM · $69.9611:40 AM · $70.6911:45 AM · $70.7211:50 AM · $70.6611:55 AM · $71.4812:00 PM · $70.7512:05 PM · $70.6412:10 PM · $70.8512:15 PM · $70.8512:20 PM · $71.1512:25 PM · $71.5912:30 PM · $71.6612:35 PM · $71.8212:40 PM · $71.7112:45 PM · $72.1912:50 PM · $71.9412:55 PM · $72.131:00 PM · $72.501:05 PM · $72.461:10 PM · $72.231:15 PM · $72.241:20 PM · $72.131:25 PM · $72.221:30 PM · $72.501:35 PM · $72.411:40 PM · $72.571:45 PM · $72.691:50 PM · $72.841:55 PM · $72.812:00 PM · $72.452:05 PM · $72.002:10 PM · $72.262:15 PM · $71.412:20 PM · $71.622:25 PM · $71.792:30 PM · $71.602:35 PM · $71.442:40 PM · $71.282:45 PM · $71.342:50 PM · $71.632:55 PM · $71.773:00 PM · $71.913:05 PM · $71.673:10 PM · $72.063:15 PM · $71.833:20 PM · $71.943:25 PM · $72.333:30 PM · $72.573:35 PM · $72.733:40 PM · $72.743:45 PM · $72.673:50 PM · $72.753:55 PM · $72.684:00 PM · $72.554:05 PM · $72.534:10 PM · $72.514:15 PM · $72.594:20 PM · $72.524:25 PM · $72.534:30 PM · $72.554:35 PM · $72.694:40 PM · $72.414:45 PM · $72.494:50 PM · $72.404:55 PM · $72.205:00 PM · $72.255:05 PM · $72.205:10 PM · $72.205:15 PM · $72.005:20 PM · $72.105:25 PM · $72.085:30 PM · $72.075:35 PM · $72.055:40 PM · $72.105:45 PM · $72.105:50 PM · $72.055:55 PM · $72.056:00 PM · $71.806:05 PM · $71.816:10 PM · $71.916:15 PM · $71.936:20 PM · $71.946:25 PM · $71.866:30 PM · $71.926:35 PM · $71.916:40 PM · $71.906:45 PM · $71.856:50 PM · $71.826:55 PM · $71.817:00 PM · $71.997:05 PM · $71.957:10 PM · $71.997:15 PM · $72.007:20 PM · $71.927:25 PM · $71.847:30 PM · $71.857:35 PM · $72.047:40 PM · $71.937:45 PM · $71.857:50 PM · $72.007:55 PM · $72.02
AI sentiment, last 36h · averaged over 11 stories · 67/100 bullish
AI sentiment 67/100 (bullish)0 · bearish50bullish · 100

The headlines behind the move

Story flow · 8 stories on the wire, last 36h · hover or tap a dot for the headline
36h ago24h ago12h agopublishTipRanks · sentiment 67 · ‘Prepare for What’s Coming,’ Says Investor About Tempus AI StockTipRanks · 67‘Prepare for What’s Coming,’ Says Investor About Tempus AI StockSeeking Alpha · sentiment 73 · Tempus AI Just Had Their Entire Strategy Validated By Moderna's Vaccine AdvanceSeeking Alpha · 73Tempus AI Just Had Their Entire Strategy Validated By Moderna's Vaccine AdvanceThe Fly · sentiment 67 · Tempus AI price target raised to $80 from $70 at BTIGThe Fly · 67Tempus AI price target raised to $80 from $70 at BTIGThe Fly · sentiment 62 · Tempus AI rises 9.5%The Fly · 62Tempus AI rises 9.5%The Fly · sentiment 62 · Tempus AI rises 10.2%The Fly · 62Tempus AI rises 10.2%Investing.com Markets · sentiment 50 · Why is Tempus AI stock surging today?Investing.com Markets · 50Why is Tempus AI stock surging today?Stocktwits News · sentiment 61 · TEM Stock On Track For Best Week In 4 Months Following Personalis Deal SpotlightStocktwits News · 61TEM Stock On Track For Best Week In 4 Months Following Personalis Deal SpotlightStocktwits News · sentiment 73 · SLS, IBRX Stocks In Focus: Analyst Says Moderna-Merck Cancer Vaccine Success ‘Bodes Well’ For OncologyStocktwits News · 73SLS, IBRX Stocks In Focus: Analyst Says Moderna-Merck Cancer Vaccine Success ‘Bodes Well’…
23d agoStocktwits NewsBULLISH 73Product/PR

SLS, IBRX Stocks In Focus: Analyst Says Moderna-Merck Cancer Vaccine Success ‘Bodes Well’ For Oncology

Moderna soared 177% Wednesday, while Merck gained 13% and the rally spread to BioNTech, Arcturus, Tempus AI and Novavax.

23d agoStocktwits NewsBULLISH 61Analyst

TEM Stock On Track For Best Week In 4 Months Following Personalis Deal Spotlight

BTIG analyst Mark Massaro raised the firm’s price target on Tempus AI to $80 from $70 and kept a Buy rating.

23d agoInvesting.com MarketsNEUTRAL 50General

Why is Tempus AI stock surging today?

Why is Tempus AI stock surging today?

23d agoThe FlyBULLISH 62General

Tempus AI rises 10.2%

23d agoThe FlyBULLISH 62General

Tempus AI rises 9.5%

24d agoThe FlyBULLISH 67Analyst

Tempus AI price target raised to $80 from $70 at BTIG

24d agoSeeking AlphaBULLISH 73Product/PR

Tempus AI Just Had Their Entire Strategy Validated By Moderna's Vaccine Advance

Tempus AI remains a strong buy, driven by its unique flywheel business model and recent validation of its technology via the Personalis acquisition. Learn more about TEM stock here.

24d agoTipRanksBULLISH 67General

‘Prepare for What’s Coming,’ Says Investor About Tempus AI Stock

Tempus AI (NASDAQ:TEM) stock is soaring about 22% on Wednesday, with Moderna’s huge melanoma win giving investors a new reason to reconsider the value of Tempus’ pe...

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More on TEM: full news and sentiment history. Sentiment scores are AI-derived research signals, not financial advice.

Earlier TEM move explainers: 2026-09-02 · 2026-08-31 · 2026-08-25 · 2026-08-24 · 2026-08-21 · 2026-08-20 · 2026-08-19