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Movers explained · 2026-09-04

Archived explainer. For the current picture see today's TYRA page.

Why Is TYRA BIOSCIENCES INC (TYRA) Stock Up Today?

By the Top Tier Newswire AI Desk · September 4, 2026 at 10:58 AM ET · reviewed against 1 wire stories

TYRA BIOSCIENCES INC (TYRA) is up +16.17% in the latest session. Our newswire has captured 1 story on TYRA across 1 source in the last 36 hours, with AI sentiment reading mixed (avg 56/100).

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Why TYRA stock is up today

TYRA stock surged 16.17% to $28.88 in a volatile session driven by the announcement that Tyra Biosciences will host a conference call on September 9 to discuss initial results from the Phase 2 SURF302 study of oral Dabogratinib for IR NMIBC. The stock opened with a modest 1.0% gap up and climbed steadily throughout the session, reaching a high of $29.35 before settling at $28.86. The move reflects investor anticipation of the clinical data and the company's progress in its pipeline.

What Happened

Tyra Biosciences announced it will host a conference call to discuss initial results from the Phase 2 SURF302 study of oral Dabogratinib for the treatment of intermediate-risk non-muscle invasive bladder cancer (IR NMIBC). The call is scheduled for September 9 and will include a webcast. The company is a clinical-stage biotechnology firm focused on developing precision medicines. The announcement follows a recent earnings report for the second quarter that showed an EPS of $(0.69), which missed the $(0.65) estimate. Despite the earnings miss, the clinical development update appears to have shifted investor focus to the potential of Dabogratinib.

What The Data Shows

The stock has traded between $24.51 and $29.35 during the session, with a volume of 0.3 million shares, which is 0.4 times the 3-month daily average. The unusual options activity includes two notable prints, with $2.0 million in call premium and no put premium. The largest single print was $1.4 million. Additionally, the stock printed 22 fresh 52-week highs on September 4. The 30-day average sentiment score is 52 out of 100, while the last 7 days show an improved score of 56 out of 100.

What To Watch

Investors should monitor the conference call on September 9 when Tyra Biosciences will present initial results from the SURF302 study. The data could influence further investor sentiment and potentially impact the stock's trajectory.

AI-assisted analysis composed exclusively from headlines and data on the Top Tier newswire. Public view is delayed 4 hours from real time. Not financial advice.

TYRA by the numbers

Last: $28.88Session: +16.17%7 sessions: +10.30%Coverage: 1 stories / 1 sourcesAI sentiment: 56/100 (mixed)Mkt cap: $1.5B52w: $11.70 to $40.65
TYRA · Sep 4 session (5-min) · +15.25% vs prior close · updated 8:56 PM ET
$24.50$27.16$29.81prev close $24.86$28.658:00 AM10:08 AM12:17 PM2:26 PM4:35 PM8:00 AM · $25.508:15 AM · $25.488:20 AM · $25.018:50 AM · $26.008:55 AM · $25.509:20 AM · $24.859:30 AM · $24.799:35 AM · $24.999:40 AM · $25.079:45 AM · $25.199:50 AM · $25.529:55 AM · $25.7910:00 AM · $26.4310:05 AM · $26.5810:10 AM · $26.7610:15 AM · $26.6810:20 AM · $26.6610:25 AM · $27.3910:30 AM · $27.0010:35 AM · $27.0810:40 AM · $27.4110:45 AM · $27.3510:50 AM · $28.4410:55 AM · $28.6711:00 AM · $28.7311:05 AM · $27.9311:10 AM · $27.6611:15 AM · $28.2711:20 AM · $28.5911:25 AM · $28.6511:30 AM · $28.1711:35 AM · $28.1811:40 AM · $28.1811:45 AM · $28.1711:50 AM · $28.2511:55 AM · $28.0512:00 PM · $28.5812:05 PM · $28.5212:10 PM · $28.4112:15 PM · $28.3812:20 PM · $28.3112:25 PM · $28.3812:30 PM · $28.4412:35 PM · $28.3412:40 PM · $28.2512:45 PM · $28.1812:50 PM · $28.2412:55 PM · $28.381:00 PM · $28.401:05 PM · $28.181:10 PM · $27.931:15 PM · $27.921:20 PM · $27.941:25 PM · $27.791:30 PM · $27.801:35 PM · $28.051:40 PM · $28.101:45 PM · $28.181:50 PM · $28.571:55 PM · $28.712:00 PM · $28.672:05 PM · $28.612:10 PM · $28.472:15 PM · $28.492:20 PM · $28.442:25 PM · $28.342:30 PM · $28.452:35 PM · $28.642:40 PM · $28.722:45 PM · $28.882:50 PM · $28.972:55 PM · $29.093:00 PM · $29.173:05 PM · $29.193:10 PM · $29.433:15 PM · $29.323:20 PM · $29.523:25 PM · $29.393:30 PM · $29.413:35 PM · $29.253:40 PM · $29.373:45 PM · $29.303:50 PM · $29.343:55 PM · $28.564:00 PM · $28.654:10 PM · $28.654:35 PM · $28.65
AI sentiment, last 36h · averaged over 1 story · 56/100 bullish
AI sentiment 56/100 (bullish)0 · bearish50bullish · 100

The headlines behind the move

Story flow · 1 story on the wire, last 36h · hover or tap a dot for the headline
36h ago24h ago12h agopublishPR Newswire · sentiment 56 · Tyra Biosciences to Host Conference Call on Initial Results of Oral Dabogratinib from the SURF302 Phase 2 Study for IR NMIBC on September 9, 2026PR Newswire · 56Tyra Biosciences to Host Conference Call on Initial Results of Oral Dabogratinib from the…
9d agoPR NewswireBULLISH 56Product/PR

Tyra Biosciences to Host Conference Call on Initial Results of Oral Dabogratinib from the SURF302 Phase 2 Study for IR NMIBC on September 9, 2026

CARLSBAD, Calif., Sept. 4, 2026 /PRNewswire/ -- Tyra Biosciences, Inc. (Nasdaq: TYRA), a clinical-stage biotechnology company focused on developing next-generation precision medicines that target large opportunities in Fibroblast Growth Factor Receptor (FGFR) biology, today announced that...

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More on TYRA: full news and sentiment history. Sentiment scores are AI-derived research signals, not financial advice.

Earlier TYRA move explainers: 2026-09-11 · 2026-09-10 · 2026-09-09 · 2026-09-08 · 2026-09-04