TOP TIERMARKET NEWSWIRE
Movers explained · 2026-08-28

Archived explainer. For the current picture see today's RVMD page.

Why Is REVOLUTION MEDICINES (RVMD) Stock Down Today?

By the Top Tier Newswire AI Desk · August 28, 2026 at 11:01 AM ET · reviewed against 15 wire stories

REVOLUTION MEDICINES (RVMD) is down -6.29% in the latest session. Our newswire has captured 15 stories on RVMD across 8 sources in the last 36 hours, with AI sentiment reading bullish (avg 65/100).

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RVMD stock fell 6.29% to $207.25 in afternoon trading on Friday, reversing from a small opening gap higher. The decline followed a series of analyst price target increases and a recent FDA approval of its pancreatic cancer drug, Rasonque, which failed to sustain investor confidence amid broader selling pressure from insiders and a high short-term valuation.

What Happened

Revolution Medicines received FDA approval for Rasonque, a first-of-its-kind targeted therapy for pancreatic cancer, which triggered a wave of analyst upgrades in recent days. Guggenheim and UBS both raised their price targets for the stock, with Guggenheim setting a new $275 target and UBS raising its target to $265. Despite these developments, the stock opened slightly higher at $222.70 but quickly reversed course, hitting a session low of $207.00 by midday. The decline accelerated as insider selling continued, with CEO Mark Goldsmith and other insiders reporting sales on August 21. The stock closed the session near its low, with volume at 0.5 million shares, or 20% of its 3-month average.

What The Data Shows

The stock has traded between $35.64 and $224.31 over the past 52 weeks and is currently valued at a market cap of $46.2 billion. Despite the recent FDA milestone, the company remains unprofitable, with a trailing twelve-month EPS of -8.92 and a revenue decline of 97.2%. The stock has moved only 0.6% over the last eight sessions, from $216.00 to $217.40. Insiders have sold a total of $54.5 million in the last 90 days, with no insider purchases recorded. Additionally, the stock printed 26 fresh 52-week lows on August 28, indicating ongoing pressure from short sellers and profit-taking.

What To Watch

Revolution Medicines does not have an upcoming earnings date listed. Investors should monitor the breadth of analyst coverage and any further insider activity for signs of conviction in the stock’s long-term prospects.

AI-assisted analysis composed exclusively from headlines and data on the Top Tier newswire. Public view is delayed 4 hours from real time. Not financial advice.

RVMD by the numbers

Last: $207.25Session: -6.29%7 sessions: -3.16%Coverage: 15 stories / 8 sourcesAI sentiment: 65/100 (bullish)Mkt cap: $46.2B52w: $35.64 to $224.31
RVMD · Aug 28 session (5-min) · -5.66% vs prior close · updated 8:44 PM ET
$205$215$224prev close $221.15$208.637:00 AM10:13 AM1:27 PM4:41 PM7:55 PM7:00 AM · $222.707:05 AM · $222.707:15 AM · $221.917:40 AM · $221.257:45 AM · $221.158:00 AM · $221.878:50 AM · $221.719:00 AM · $221.949:05 AM · $221.009:15 AM · $221.509:20 AM · $222.299:25 AM · $222.999:30 AM · $215.809:35 AM · $216.249:40 AM · $216.629:45 AM · $214.989:50 AM · $214.449:55 AM · $214.0510:00 AM · $213.6510:05 AM · $210.9010:10 AM · $211.5310:15 AM · $211.4310:20 AM · $211.1510:25 AM · $210.0510:30 AM · $210.3110:35 AM · $209.4510:40 AM · $209.1210:45 AM · $208.7810:50 AM · $208.4410:55 AM · $207.1411:00 AM · $207.4411:05 AM · $207.5011:10 AM · $208.0011:15 AM · $207.6711:20 AM · $207.3611:25 AM · $207.2911:30 AM · $207.9811:35 AM · $207.9911:40 AM · $208.1011:45 AM · $207.2211:50 AM · $206.7311:55 AM · $206.2912:00 PM · $206.6012:05 PM · $207.6012:10 PM · $207.2512:15 PM · $206.0912:20 PM · $206.4012:25 PM · $206.7812:30 PM · $206.5612:35 PM · $206.7612:40 PM · $206.7012:45 PM · $206.4512:50 PM · $206.1512:55 PM · $206.641:00 PM · $206.681:05 PM · $206.721:10 PM · $207.061:15 PM · $207.341:20 PM · $207.721:25 PM · $207.931:30 PM · $207.611:35 PM · $207.491:40 PM · $207.641:45 PM · $207.541:50 PM · $207.881:55 PM · $208.192:00 PM · $207.802:05 PM · $207.992:10 PM · $208.222:15 PM · $208.402:20 PM · $208.002:25 PM · $207.002:30 PM · $207.282:35 PM · $207.342:40 PM · $207.352:45 PM · $207.562:50 PM · $207.812:55 PM · $207.693:00 PM · $207.603:05 PM · $207.793:10 PM · $208.013:15 PM · $208.323:20 PM · $208.243:25 PM · $208.313:30 PM · $208.633:35 PM · $208.593:40 PM · $208.773:45 PM · $208.973:50 PM · $208.703:55 PM · $207.884:00 PM · $207.884:10 PM · $208.944:50 PM · $208.215:30 PM · $208.175:40 PM · $207.945:45 PM · $208.506:05 PM · $208.206:55 PM · $208.157:30 PM · $208.707:35 PM · $208.607:45 PM · $208.607:55 PM · $208.63
AI sentiment, last 36h · averaged over 15 stories · 65/100 bullish
AI sentiment 65/100 (bullish)0 · bearish50bullish · 100

The headlines behind the move

Story flow · 8 stories on the wire, last 36h · hover or tap a dot for the headline
36h ago24h ago12h agopublishTipRanks · sentiment 68 · Revolution Medicines Stock (RVMD) Gets Price Target Hike on New Revenue-Generating Cancer DrugTipRanks · 68Revolution Medicines Stock (RVMD) Gets Price Target Hike on New Revenue-Generating Cancer…Stocktwits News · sentiment 56 · Revolution Medicine’s $39,800-Monthly Cancer Drug Puts Access In Focus — CEO Goldsmith Expects Insurers To Move ‘Swiftly’ To Provide CoverageStocktwits News · 56Revolution Medicine’s $39,800-Monthly Cancer Drug Puts Access In Focus — CEO Goldsmith Ex…Seeking Alpha · sentiment 73 · Revolution Medicines, Inc. (RVMD) Discusses FDA Approval of RASONQUE for Metastatic Pancreatic Cancer and Implications for RAS-Driven Therapy TranscriptSeeking Alpha · 73Revolution Medicines, Inc. (RVMD) Discusses FDA Approval of RASONQUE for Metastatic Pancr…WSJ · sentiment 73 · Why the Drugmaker Behind a Pancreatic Cancer Breakthrough Stayed IndependentWSJ · 73Why the Drugmaker Behind a Pancreatic Cancer Breakthrough Stayed IndependentThe Motley Fool · sentiment 82 · Revolution Medicines Won FDA Approval One Month After Filing. Analysts See $11.5 Billion in Peak Sales. Is the Stock Still a Buy After Skyrocketing More Than 5X?The Motley Fool · 82Revolution Medicines Won FDA Approval One Month After Filing. Analysts See $11.5 Billion …The Fly · sentiment 61 · Revolution Medicines price target raised to $275 from $240 at GuggenheimThe Fly · 61Revolution Medicines price target raised to $275 from $240 at GuggenheimThe Fly · sentiment 61 · Revolution Medicines price target raised to $265 from $220 at UBSThe Fly · 61Revolution Medicines price target raised to $265 from $220 at UBSInvesting.com Analyst Ratings · sentiment 63 · Guggenheim raises Revolution stock price target on drug pricing, launch timingInvesting.com Analyst Ratings · 63Guggenheim raises Revolution stock price target on drug pricing, launch timing
15d agoInvesting.com Analyst RatingsBULLISH 63Analyst

Guggenheim raises Revolution stock price target on drug pricing, launch timing

Guggenheim raises Revolution stock price target on drug pricing, launch timing

16d agoThe FlyBULLISH 61Analyst

Revolution Medicines price target raised to $265 from $220 at UBS

16d agoThe FlyBULLISH 61Analyst

Revolution Medicines price target raised to $275 from $240 at Guggenheim

16d agoThe Motley FoolBULLISH 82Product/PR

Revolution Medicines Won FDA Approval One Month After Filing. Analysts See $11.5 Billion in Peak Sales. Is the Stock Still a Buy After Skyrocketing More Than 5X?

The biotech's Rasonque is already available for prescription.

16d agoWSJBULLISH 73Product/PR

Why the Drugmaker Behind a Pancreatic Cancer Breakthrough Stayed Independent

Revolution Medicines attracted takeover interest but decided to go it alone. This week’s FDA approval of its pancreatic cancer pill is the payoff.

16d agoSeeking AlphaBULLISH 73Product/PR

Revolution Medicines, Inc. (RVMD) Discusses FDA Approval of RASONQUE for Metastatic Pancreatic Cancer and Implications for RAS-Driven Therapy Transcript

Revolution Medicines, Inc. (RVMD) Discusses FDA Approval of RASONQUE for Metastatic Pancreatic Cancer and Implications for RAS-Driven Therapy August 26,...

16d agoStocktwits NewsBULLISH 56Product/PR

Revolution Medicine’s $39,800-Monthly Cancer Drug Puts Access In Focus — CEO Goldsmith Expects Insurers To Move ‘Swiftly’ To Provide Coverage

CEO Mark Goldsmith said discussions with insurers gave the company confidence that they understand the drug’s clinical value.

16d agoTipRanksBULLISH 68Analyst

Revolution Medicines Stock (RVMD) Gets Price Target Hike on New Revenue-Generating Cancer Drug

Shares in oncology drugs group Revolution Medicines ($RVMD) were healthier again today after a leading analyst said its new pancreatic cancer drug would be a revenu...

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More on RVMD: full news and sentiment history. Sentiment scores are AI-derived research signals, not financial advice.

Earlier RVMD move explainers: 2026-08-28 · 2026-08-26 · 2026-08-17