TOP TIERMARKET NEWSWIRE
Movers explained · 2026-10-28

Archived explainer. For the current picture see today's REPL page.

Why Is REPLIMUNE GROUP INC (REPL) Stock Up Today?

By the Top Tier Newswire AI Desk · October 28, 2026 at 2:26 PM ET · reviewed against 3 wire stories

REPLIMUNE GROUP INC (REPL) is up +21.42% in the latest session. Our newswire has captured 3 stories on REPL across 3 sources in the last 36 hours, with AI sentiment reading mixed (avg 55/100).

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Replimune Group shares surged 21.42% to close at $15.85 on Tuesday. The primary driver was the company’s fiscal second quarter 2027 earnings report, which showed a GAAP loss per share of $0.54, beating the consensus estimate of $0.77.

What Happened

Replimune filed a Form 8-K with the SEC on October 28, 2026, disclosing its financial results. The company reported that cash balances rose to $307.8 million while research and development costs declined. This performance followed the recent commercial availability of TUDRIQEV in the United States for the treatment of unresectable advanced cutaneous melanoma. The stock had been relatively flat over the preceding eight sessions, moving from $13.10 to $13.04 before the announcement.

What The Data Shows

The stock opened the session at $13.08 and hit a low of $12.30 at 9:25 AM ET before rallying to a session high of $15.99 at 2:20 PM ET. Trading volume reached 3.1 million shares, which is 0.8 times the three-month daily average. The company has a market capitalization of $1.2 billion and remains unprofitable with a trailing twelve-month EPS of $3.15. The stock’s beta is 0.94, and it currently trades within its 52-week range of $1.50 to $16.33. On the day of the report, the stock printed 36 fresh 52-week highs and 6 fresh 52-week lows. Recent insider activity includes five sales totaling $1.0 million over the last 90 days, with no buys recorded. The most recent Form 4 filings show sales by CEO Sushil Patel and CFO Emily Luisa Hill in August 2026.

What To Watch

Investors will monitor the company’s coverage breadth and future guidance following the earnings release. The stock’s position near its 52-week high suggests continued momentum, though the lack of recent insider buying may temper expectations for near-term support.

AI-assisted analysis composed exclusively from headlines and data on the Top Tier newswire. Public view is delayed 4 hours from real time. Not financial advice.

REPL by the numbers

Last: $15.85Session: +21.42%7 sessions: -0.46%Coverage: 3 stories / 3 sourcesAI sentiment: 55/100 (mixed)Mkt cap: $1.2B52w: $1.50 to $16.33
REPL · today's session (5-min) · +21.03% vs prior close · updated 7:19 PM ET
$12.40$14.53$16.65prev close $13.05$15.797:00 AM10:03 AM1:07 PM4:11 PM7:15 PM7:00 AM · $12.997:30 AM · $13.007:45 AM · $13.008:15 AM · $12.908:25 AM · $12.808:40 AM · $12.718:45 AM · $12.808:50 AM · $12.809:25 AM · $12.989:30 AM · $12.899:35 AM · $12.639:40 AM · $13.029:45 AM · $12.889:50 AM · $12.779:55 AM · $12.7910:00 AM · $12.8310:05 AM · $12.8810:10 AM · $13.0610:15 AM · $13.2110:20 AM · $13.3610:25 AM · $13.7310:30 AM · $13.8210:35 AM · $13.8310:40 AM · $14.0310:45 AM · $14.1810:50 AM · $14.3010:55 AM · $14.3911:00 AM · $14.5011:05 AM · $14.4611:10 AM · $14.5311:15 AM · $14.5711:20 AM · $14.3911:25 AM · $14.2811:30 AM · $14.5811:35 AM · $14.6011:40 AM · $14.4911:45 AM · $15.0211:50 AM · $14.9711:55 AM · $14.9912:00 PM · $15.0312:05 PM · $14.9912:10 PM · $14.8712:15 PM · $14.9712:20 PM · $14.9512:25 PM · $14.8412:30 PM · $14.8012:35 PM · $14.5912:40 PM · $14.7112:45 PM · $14.6012:50 PM · $14.7012:55 PM · $14.951:00 PM · $15.041:05 PM · $15.131:10 PM · $15.241:15 PM · $15.211:20 PM · $15.221:25 PM · $15.111:30 PM · $15.181:35 PM · $15.161:40 PM · $15.041:45 PM · $15.211:50 PM · $15.061:55 PM · $15.302:00 PM · $15.282:05 PM · $15.332:10 PM · $15.402:15 PM · $15.462:20 PM · $15.872:25 PM · $15.932:30 PM · $16.162:35 PM · $16.432:40 PM · $16.202:45 PM · $16.202:50 PM · $16.322:55 PM · $16.203:00 PM · $16.263:05 PM · $16.033:10 PM · $16.003:15 PM · $16.053:20 PM · $16.153:25 PM · $16.263:30 PM · $16.333:35 PM · $16.253:40 PM · $16.273:45 PM · $16.233:50 PM · $15.913:55 PM · $16.074:00 PM · $15.854:05 PM · $15.594:10 PM · $15.824:15 PM · $15.804:25 PM · $15.734:30 PM · $15.724:40 PM · $15.744:45 PM · $15.824:50 PM · $15.815:05 PM · $15.825:35 PM · $15.805:45 PM · $15.736:35 PM · $15.807:10 PM · $15.727:15 PM · $15.79
AI sentiment, last 36h · averaged over 3 stories · 55/100 bullish
AI sentiment 55/100 (bullish)0 · bearish50bullish · 100

The headlines behind the move

Story flow · 3 stories on the wire, last 36h · hover or tap a dot for the headline
36h ago24h ago12h agopublishStockTitan · sentiment 52 · Replimune Reports Fiscal Second Quarter 2027 Financial Results and Provides Corporate UpdateStockTitan · 52Replimune Reports Fiscal Second Quarter 2027 Financial Results and Provides Corporate UpdateSEC 8-K · sentiment 50 · Replimune Group, Inc. (REPL) files 8-KSEC 8-K · 50Replimune Group, Inc. (REPL) files 8-KSeeking Alpha · sentiment 64 · Replimune Group GAAP EPS of -$0.54 beats by $0.21Seeking Alpha · 64Replimune Group GAAP EPS of -$0.54 beats by $0.21
12h agoSeeking AlphaBULLISH 64Earnings

Replimune Group GAAP EPS of -$0.54 beats by $0.21

Replimune Q2 earnings beat estimates, with cash rising to $307.8M and R&D costs falling.

12h agoSEC 8-KNEUTRAL 50General

Replimune Group, Inc. (REPL) files 8-K

Filed: 2026-10-28 AccNo: 0001104659-26-119354 Size: 272 KB Item 2.02: Results of Operations and Financial Condition Item 9.01: Financial Statements and Exhibits

12h agoStockTitanNEUTRAL 52Earnings

Replimune Reports Fiscal Second Quarter 2027 Financial Results and Provides Corporate Update

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More on REPL: full news and sentiment history. Sentiment scores are AI-derived research signals, not financial advice.

Earlier REPL move explainers: 2026-10-28 · 2026-09-29 · 2026-09-11 · 2026-09-10