TOP TIERMARKET NEWSWIRE
Movers explained · 2026-08-06

Archived explainer. For the current picture see today's INSM page.

Why Is INSMED INC (INSM) Stock Up Today?

By the Top Tier Newswire AI Desk · August 6, 2026 at 2:48 PM ET · reviewed against 12 wire stories

INSMED INC (INSM) is up +31.53% in the latest session. Our newswire has captured 12 stories on INSM across 7 sources in the last 36 hours, with AI sentiment reading bullish (avg 65/100).

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Why INSM stock is up today

INSM stock surged 31.53% to $130.24 in a single session driven by a combination of raised revenue guidance and strong Q2 2026 performance. The company announced a significant increase in its revenue forecast for BRINSUPRI (brensocatib) and highlighted robust sales growth. The stock opened with a modest 1.5% gap up and climbed steadily throughout the session, reaching an intraday high of $137.70 before settling near $130.16.

What Happened

The sharp rise in INSM shares came after Insmed reported a standout second quarter with 296% revenue growth and raised its revenue guidance for BRINSUPRI. The company now forecasts $1.25 billion to $1.40 billion in BRINSUPRI sales, up from previous estimates. Insmed also raised its peak sales outlook for its three lead programs to more than $14 billion. Jefferies upgraded the stock, raising its price target to $175 from $160. The Q2 2026 earnings call highlighted progress in the company’s respiratory therapies and strong performance across its pipeline.

What The Data Shows

The stock opened at $100.47 and traded as high as $137.70 during the session. Volume reached 6.9 million shares, more than double the 3-month daily average. Over the last 8 sessions, the stock has risen 25.5%, from $104.13 to $130.71. Unusual options activity was noted, with $2.3 million in call premium versus $581,000 in put premium, including a notable $1.6 million print. In the last 90 days, insiders have sold 18 times, totaling $16.4 million, with no buys recorded.

What To Watch

The company’s Q2 2026 earnings call on August 6, 2026, provided key insights but no upcoming earnings date is scheduled. Investors will want to monitor the breadth of coverage and any further updates on BRINSUPRI’s performance or additional guidance from the company.

AI-assisted analysis composed exclusively from headlines and data on the Top Tier newswire. Public view is delayed 4 hours from real time. Not financial advice.

INSM by the numbers

Last: $130.24Session: +31.53%7 sessions: +25.53%Coverage: 12 stories / 7 sourcesAI sentiment: 65/100 (bullish)Mkt cap: $21.4B52w: $90.39 to $212.75
INSM · Aug 6 session (5-min) · +33.31% vs prior close · updated 8:44 PM ET
$96.71$118$140prev close $99.02$132.007:00 AM10:03 AM1:07 PM4:11 PM7:15 PM7:00 AM · $109.507:05 AM · $116.757:10 AM · $116.397:15 AM · $115.177:20 AM · $118.007:25 AM · $118.017:30 AM · $118.387:35 AM · $120.007:40 AM · $121.237:45 AM · $120.007:50 AM · $121.957:55 AM · $121.998:00 AM · $123.918:05 AM · $130.198:10 AM · $128.068:15 AM · $126.008:20 AM · $125.058:25 AM · $125.518:30 AM · $126.008:35 AM · $125.008:40 AM · $125.008:45 AM · $126.218:50 AM · $126.538:55 AM · $126.009:00 AM · $127.479:05 AM · $127.489:10 AM · $127.059:15 AM · $127.959:20 AM · $128.709:25 AM · $129.209:30 AM · $131.409:35 AM · $132.049:40 AM · $131.409:45 AM · $134.719:50 AM · $135.479:55 AM · $135.9010:00 AM · $137.2810:05 AM · $137.5910:10 AM · $133.7410:15 AM · $131.9710:20 AM · $130.0710:25 AM · $129.9510:30 AM · $131.1610:35 AM · $131.6710:40 AM · $131.7110:45 AM · $131.7410:50 AM · $131.1310:55 AM · $131.0911:00 AM · $131.0511:05 AM · $129.8711:10 AM · $131.3411:15 AM · $131.4811:20 AM · $131.1311:25 AM · $130.5111:30 AM · $130.8911:35 AM · $131.4711:40 AM · $130.6911:45 AM · $130.7911:50 AM · $130.6511:55 AM · $130.6112:00 PM · $129.8812:05 PM · $129.9612:10 PM · $130.0312:15 PM · $129.9612:20 PM · $129.8812:25 PM · $129.9112:30 PM · $129.5612:35 PM · $129.6312:40 PM · $129.5012:45 PM · $129.6012:50 PM · $129.8812:55 PM · $129.951:00 PM · $130.741:05 PM · $130.761:10 PM · $131.291:15 PM · $131.441:20 PM · $131.761:25 PM · $131.541:30 PM · $131.471:35 PM · $131.661:40 PM · $132.061:45 PM · $132.051:50 PM · $131.751:55 PM · $131.412:00 PM · $131.192:05 PM · $131.112:10 PM · $131.322:15 PM · $131.192:20 PM · $131.562:25 PM · $131.252:30 PM · $130.742:35 PM · $130.632:40 PM · $130.532:45 PM · $130.182:50 PM · $130.112:55 PM · $130.603:00 PM · $130.013:05 PM · $129.093:10 PM · $129.753:15 PM · $129.553:20 PM · $130.003:25 PM · $130.733:30 PM · $130.413:35 PM · $130.313:40 PM · $130.563:45 PM · $130.313:50 PM · $129.963:55 PM · $132.604:00 PM · $132.254:15 PM · $132.484:30 PM · $132.444:35 PM · $132.104:40 PM · $133.004:45 PM · $132.004:50 PM · $133.304:55 PM · $132.555:10 PM · $133.715:15 PM · $132.705:20 PM · $132.655:40 PM · $132.505:55 PM · $131.486:20 PM · $132.886:25 PM · $131.476:30 PM · $132.396:40 PM · $132.007:05 PM · $131.517:15 PM · $132.00
AI sentiment, last 36h · averaged over 12 stories · 65/100 bullish
AI sentiment 65/100 (bullish)0 · bearish50bullish · 100

The headlines behind the move

Story flow · 8 stories on the wire, last 36h · hover or tap a dot for the headline
36h ago24h ago12h agopublishThe Fly · sentiment 63 · Insmed Rises 37 1The Fly · 63Insmed Rises 37 1Yahoo Finance · sentiment 73 · Insmed Catapults 30%, Leading A Biotech Rally; But Mirum Takes A BathYahoo Finance · 73Insmed Catapults 30%, Leading A Biotech Rally; But Mirum Takes A BathInvestorsHub · sentiment 73 · Insmed Raises BRINSUPRI Revenue Guidance After Strong Q2 Growth and Expands Peak Sales OutlookInvestorsHub · 73Insmed Raises BRINSUPRI Revenue Guidance After Strong Q2 Growth and Expands Peak Sales Ou…Seeking Alpha · sentiment 76 · Insmed surges on raised Brinsupri sales forecast, Q2 beatsSeeking Alpha · 76Insmed surges on raised Brinsupri sales forecast, Q2 beatsMarketChameleon · sentiment 82 · Insmed Lifts Revenue Targets, Reports Breakout Second Quarter on Brensocatib and Pipeline Progress August 6, 2026MarketChameleon · 82Insmed Lifts Revenue Targets, Reports Breakout Second Quarter on Brensocatib and Pipeline…Seeking Alpha · sentiment 50 · Insmed Incorporated (INSM) Q2 2026 Earnings Call TranscriptSeeking Alpha · 50Insmed Incorporated (INSM) Q2 2026 Earnings Call TranscriptThe Fly · sentiment 68 · Insmed rises 31.9%The Fly · 68Insmed rises 31.9%The Fly · sentiment 63 · Insmed price target raised to $175 from $160 at JefferiesThe Fly · 63Insmed price target raised to $175 from $160 at Jefferies
4d agoThe FlyBULLISH 63Analyst

Insmed price target raised to $175 from $160 at Jefferies

4d agoThe FlyBULLISH 68Earnings

Insmed rises 31.9%

4d agoSeeking AlphaNEUTRAL 50Earnings

Insmed Incorporated (INSM) Q2 2026 Earnings Call Transcript

Insmed Incorporated (INSM) Q2 2026 Earnings Call August 6, 2026 8:00 AM EDTCompany ParticipantsBryan Dunn - Vice President of Investor RelationsWilliam...

4d agoMarketChameleonBULLISH 82Earnings

Insmed Lifts Revenue Targets, Reports Breakout Second Quarter on Brensocatib and Pipeline Progress August 6, 2026

Insmed delivered a standout Q2 2026 with 296% revenue growth, surging BRINSUPRI (brensocatib) sales, and heightened guidance for its flagship respiratory therapies. The company projects peak sales of $14 billion for its top three programs and outlined significant pipeline advancements in PAH, MAC lung disease, and rare disorders.

4d agoSeeking AlphaBULLISH 76Earnings

Insmed surges on raised Brinsupri sales forecast, Q2 beats

Insmed stock jumps 33% as Brinsupri guidance rises to $1.25B-$1.40B; Q2 beats and peak sales seen >$7B. Read more here.

4d agoInvestorsHubBULLISH 73Earnings

Insmed Raises BRINSUPRI Revenue Guidance After Strong Q2 Growth and Expands Peak Sales Outlook

Insmed reported second-quarter 2026 revenue of $425.5 million, raised BRINSUPRI revenue guidance to $1.25-$1.40 billion and increased peak sales expectations for its three lead programmes to more than $14 billion.

4d agoYahoo FinanceBULLISH 73Earnings

Insmed Catapults 30%, Leading A Biotech Rally; But Mirum Takes A Bath

4d agoThe FlyBULLISH 63General

Insmed Rises 37 1

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More on INSM: full news and sentiment history. Sentiment scores are AI-derived research signals, not financial advice.

Earlier INSM move explainers: 2026-08-07 · 2026-08-06