TOP TIERMARKET NEWSWIRE
Movers explained · 2026-10-05

Archived explainer. For the current picture see today's GMAB page.

Why Is GENMAB A/S ADR (GMAB) Stock Up Today?

By the Top Tier Newswire AI Desk · October 5, 2026 at 2:55 PM ET · reviewed against 9 wire stories

GENMAB A/S ADR (GMAB) is up +12.23% in the latest session. Our newswire has captured 9 stories on GMAB across 6 sources in the last 36 hours, with AI sentiment reading bullish (avg 63/100).

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Why GMAB stock is up today

Genmab A/S ADR (GMAB) surged 12.23% to $39.00 on October 5, 2026, driven by a series of positive developments across its clinical pipeline. The stock opened with a modest 1.3% gap up and climbed steadily throughout the session, reaching a high of $39.30 before settling near its peak. The move reflects investor optimism over recent data from Genmab’s trials and upgraded analyst expectations.

What Happened

Genmab announced new data from its Rina-S Phase 1/2 RAINFOL-01 Part C trial, showing a 45.9% objective response rate in patients with platinum-resistant ovarian cancer. The results also indicated that 51% of responders remained in response after one year, with activity observed regardless of FRα expression levels. These findings highlight the drug’s potential in a difficult-to-treat patient population. Additionally, Genmab reported that its bispecific antibody epcoritamab, when combined with R-CHOP, demonstrated statistically significant improvement in progression-free survival in newly diagnosed diffuse large B-cell lymphoma patients in the EPCORE DLBCL-2 Phase 3 study.

Analyst activity also contributed to the rally. Guggenheim raised its price target for Genmab to $54 from $45, citing the company’s pipeline potential. HC Wainwright & Co. reiterated its Buy rating with a $40 price target. Meanwhile, Darwin Global Management disclosed a 5.11% stake in Genmab, controlling 3,188,361 shares as of September 28, 2026.

What The Data Shows

The stock’s intraday performance showed strong momentum, with volume reaching 5.8 million shares, 2.5 times the 3-month average. The session high of $39.30 marked a new 52-week high, as the stock crossed above its prior 52-week peak of $35.91. Over the last 8 sessions, the stock had already risen 3.3% from $34.83 to $35.99. The 30-day average sentiment has improved from 57/100 to 61/100, reflecting growing positive sentiment.

What To Watch

Investors will likely continue to monitor Genmab’s clinical progress, particularly for Rina-S and epcoritamab. Analyst coverage and institutional ownership changes may also influence the stock’s near-term direction.

AI-assisted analysis composed exclusively from headlines and data on the Top Tier newswire. Public view is delayed 4 hours from real time. Not financial advice.

GMAB by the numbers

Last: $39.00Session: +12.23%7 sessions: +3.34%Coverage: 9 stories / 6 sourcesAI sentiment: 63/100 (bullish)Mkt cap: $20.3BP/E: 2.752w: $23.62 to $35.91
GMAB · today's session (5-min) · +11.65% vs prior close · updated 8:08 PM ET
$34.40$37.24$40.07prev close $34.75$38.807:00 AM10:13 AM1:27 PM4:41 PM7:55 PM7:00 AM · $35.217:05 AM · $35.157:10 AM · $35.107:15 AM · $35.057:20 AM · $35.107:25 AM · $35.107:30 AM · $35.107:45 AM · $35.057:55 AM · $35.088:00 AM · $35.118:05 AM · $35.018:10 AM · $35.108:15 AM · $35.058:20 AM · $35.038:30 AM · $34.938:50 AM · $34.818:55 AM · $34.709:05 AM · $34.889:10 AM · $34.839:15 AM · $34.849:25 AM · $35.069:30 AM · $35.509:35 AM · $35.419:40 AM · $35.459:45 AM · $35.489:50 AM · $35.599:55 AM · $35.8910:00 AM · $35.9010:05 AM · $35.9110:10 AM · $35.8410:15 AM · $35.7110:20 AM · $35.7810:25 AM · $35.6110:30 AM · $35.6610:35 AM · $35.5610:40 AM · $35.7010:45 AM · $35.6510:50 AM · $35.7410:55 AM · $35.7711:00 AM · $35.7311:05 AM · $35.6711:10 AM · $35.6011:15 AM · $35.6711:20 AM · $35.6711:25 AM · $35.8511:30 AM · $35.8611:35 AM · $35.8511:40 AM · $35.8511:45 AM · $35.8811:50 AM · $35.9511:55 AM · $35.9212:00 PM · $35.8712:05 PM · $35.8012:10 PM · $35.8812:15 PM · $35.8712:20 PM · $35.9012:25 PM · $35.9812:30 PM · $35.9212:35 PM · $35.9112:40 PM · $35.9212:45 PM · $35.9512:50 PM · $35.8812:55 PM · $35.871:00 PM · $35.981:05 PM · $35.881:10 PM · $35.891:15 PM · $35.951:20 PM · $35.931:25 PM · $35.981:30 PM · $35.971:35 PM · $35.941:40 PM · $35.951:45 PM · $35.991:50 PM · $36.011:55 PM · $35.972:00 PM · $35.912:05 PM · $35.922:10 PM · $35.912:15 PM · $35.912:20 PM · $35.882:25 PM · $35.902:30 PM · $35.922:35 PM · $35.912:40 PM · $35.902:45 PM · $36.662:50 PM · $39.162:55 PM · $38.493:00 PM · $38.823:05 PM · $39.773:10 PM · $39.303:15 PM · $39.223:20 PM · $39.473:25 PM · $39.233:30 PM · $39.093:35 PM · $38.923:40 PM · $38.913:45 PM · $38.543:50 PM · $38.693:55 PM · $38.484:00 PM · $38.134:10 PM · $39.004:20 PM · $38.504:25 PM · $38.704:30 PM · $39.384:40 PM · $39.134:45 PM · $39.035:10 PM · $38.885:20 PM · $38.985:40 PM · $38.666:00 PM · $38.966:35 PM · $38.876:45 PM · $39.036:50 PM · $38.757:05 PM · $38.777:55 PM · $38.80
AI sentiment, last 36h · averaged over 9 stories · 63/100 bullish
AI sentiment 63/100 (bullish)0 · bearish50bullish · 100

The headlines behind the move

Story flow · 8 stories on the wire, last 36h · hover or tap a dot for the headline
36h ago24h ago12h agopublishThe Fly · sentiment 59 · Genmab announces Rina-S Phase 2 RAINFOL-1 trial resultsThe Fly · 59Genmab announces Rina-S Phase 2 RAINFOL-1 trial resultsInvesting.com Markets · sentiment 73 · Genmab shares jump as ovarian cancer drug shows durable responses in trialInvesting.com Markets · 73Genmab shares jump as ovarian cancer drug shows durable responses in trialInvesting.com Markets · sentiment 50 · Why is Genmab stock rallying today?Investing.com Markets · 50Why is Genmab stock rallying today?MarketChameleon · sentiment 67 · Genmab Highlights Rina-S Responses in Platinum-Resistant Ovarian Cancer, with 51% of Responders Still in Response at One Year October 5, 2026MarketChameleon · 67Genmab Highlights Rina-S Responses in Platinum-Resistant Ovarian Cancer, with 51% of Resp…Investing.com Analyst Ratings · sentiment 61 · Guggenheim raises Genmab stock price target on pipeline potentialInvesting.com Analyst Ratings · 61Guggenheim raises Genmab stock price target on pipeline potentialThe Fly · sentiment 67 · Genmab price target raised to $54 from $45 at GuggenheimThe Fly · 67Genmab price target raised to $54 from $45 at GuggenheimMarketChameleon · sentiment 50 · Genmab discloses Darwin Global stake at 5.11% of voting rightsMarketChameleon · 50Genmab discloses Darwin Global stake at 5.11% of voting rightsGlobeNewswire · sentiment 73 · Genmab and AbbVie Announce Epcoritamab in Combination with R-CHOP Demonstrates Statistically Significant Improvement in Progression-Free Survival in Patients with Newly Diagnosed Diffuse Large B-Cell LymphomaGlobeNewswire · 73Genmab and AbbVie Announce Epcoritamab in Combination with R-CHOP Demonstrates Statistica…
5h agoGlobeNewswireBULLISH 73Product/PR

Genmab and AbbVie Announce Epcoritamab in Combination with R-CHOP Demonstrates Statistically Significant Improvement in Progression-Free Survival in Patients with Newly Diagnosed Diffuse Large B-Cell Lymphoma

Company Announcement COPENHAGEN, Denmark and NORTH CHICAGO, Ill.; October 5, 2026 EPCORE DLBCL-2 is the first Phase 3 study of a bispecific antibody combination therapy to demonstrate statistically significant and...

9h agoMarketChameleonNEUTRAL 50General

Genmab discloses Darwin Global stake at 5.11% of voting rights

Genmab disclosed that Darwin Global Management Limited controls voting rights attached to 3,188,361 shares—5.11% of Genmab’s voting rights—as of September 28, 2026. The announcement is a regulatory major-shareholder notice rather than a business or pipeline update, with GMAB trading at $35.70 as of 11:04 AM.

12h agoThe FlyBULLISH 67Analyst

Genmab price target raised to $54 from $45 at Guggenheim

13h agoInvesting.com Analyst RatingsBULLISH 61Analyst

Guggenheim raises Genmab stock price target on pipeline potential

Guggenheim raises Genmab stock price target on pipeline potential

13h agoMarketChameleonBULLISH 67Product/PR

Genmab Highlights Rina-S Responses in Platinum-Resistant Ovarian Cancer, with 51% of Responders Still in Response at One Year October 5, 2026

Genmab reported Phase 1/2 RAINFOL-01 Part C results showing a confirmed 45.9% objective response rate for investigational ADC Rina-S in 109 patients with platinum-resistant ovarian cancer, with a 12.1-month median duration of response and 51% of responders still in response at one year. The company also reported a 9.5-month median progression-free survival and said activity was observed regardless of FRa expression level, including low and non-expressors, as multiple Phase 3 trials continue.

15h agoInvesting.com MarketsNEUTRAL 50General

Why is Genmab stock rallying today?

Why is Genmab stock rallying today?

16h agoInvesting.com MarketsBULLISH 73Product/PR

Genmab shares jump as ovarian cancer drug shows durable responses in trial

Genmab shares jump as ovarian cancer drug shows durable responses in trial

1d agoThe FlyBULLISH 59Product/PR

Genmab announces Rina-S Phase 2 RAINFOL-1 trial results

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More on GMAB: full news and sentiment history. Sentiment scores are AI-derived research signals, not financial advice.

Earlier GMAB move explainers: 2026-10-05