TOP TIERMARKET NEWSWIRE
Movers explained · 2026-10-30

Archived explainer. For the current picture see today's EXEL page.

Why Is EXELIXIS INC (EXEL) Stock Up Today?

By the Top Tier Newswire AI Desk · October 30, 2026 at 10:42 AM ET · reviewed against 14 wire stories

EXELIXIS INC (EXEL) is up +7.11% in the latest session. Our newswire has captured 14 stories on EXEL across 7 sources in the last 36 hours, with AI sentiment reading bullish (avg 59/100).

Public view, delayed 4h. Every headline, price and sentiment read below — and this write-up itself — reaches Pro subscribers live. Public readers see it once it clears the delay.

Exelixis shares rose 7.11% to $70.91 on Friday, driven by strong third-quarter results and a series of analyst price target hikes. The company reported that Cabozantinib sales grew 11% year over year, while its pipeline candidate zanzalintinib advanced toward FDA decisions.

What Happened

Exelixis announced its third-quarter 2026 financial results, highlighting momentum in its CABOMETYX franchise and progress in its development pipeline. The company affirmed its full-year 2026 sales guidance of $2.500 billion to $2.550 billion. Following the release, TD Cowen raised its price target to $76 from $55. Barclays also lifted its target to $54 from $49, while BMO raised its target to $60 based on the company's operating expense outlook. The stock printed 13 fresh 52-week highs on October 30, 2026.

What The Data Shows

The stock opened at $64.19, a 3.0% gap down from the prior close of $66.20, before rallying to a session high of $71.87 at 9:55 AM ET. Volume stood at 0.7 million shares, which is 0.3 times the three-month daily average. Exelixis has a market capitalization of $16.4 billion and a P/E ratio of 20.8. Trailing twelve-month revenue increased 9.2%, with a net margin of 35.3%. The stock has a beta of 0.47 and a 52-week range of $36.00 to $67.52. Over the last eight sessions, the stock moved up 1.8% from $64.39 to $65.56. Recent insider filings show one sale totaling $527,000 by Director Mary C. Beckerle on August 10, 2026, with no buys in the last 90 days.

What To Watch

Exelixis outlined a March 3, 2027 PDUFA date for zanzalintinib while advancing Wave 2 pivotal plans. Investors will monitor the company's ability to maintain its sales guidance and the progression of its pipeline milestones.

AI-assisted analysis composed exclusively from headlines and data on the Top Tier newswire. Public view is delayed 4 hours from real time. Not financial advice.

EXEL by the numbers

Last: $70.91Session: +7.11%7 sessions: +1.82%Coverage: 14 stories / 7 sourcesAI sentiment: 59/100 (bullish)Mkt cap: $16.4BP/E: 20.852w: $36.00 to $67.52
EXEL · today's session (5-min) · +4.82% vs prior close · updated 4:25 PM ET
$64.05$68.29$72.53prev close $66.20$69.397:00 AM9:15 AM11:30 AM1:45 PM4:00 PM7:00 AM · $64.507:15 AM · $64.807:40 AM · $64.607:45 AM · $64.918:45 AM · $66.129:25 AM · $68.009:30 AM · $68.699:35 AM · $70.349:40 AM · $69.899:45 AM · $71.079:50 AM · $71.299:55 AM · $71.7510:00 AM · $71.1910:05 AM · $71.3110:10 AM · $70.8810:15 AM · $70.3510:20 AM · $70.7610:25 AM · $70.7510:30 AM · $70.7510:35 AM · $70.9510:40 AM · $71.3810:45 AM · $71.5010:50 AM · $71.1810:55 AM · $71.0011:00 AM · $71.4611:05 AM · $71.5211:10 AM · $71.4411:15 AM · $71.5011:20 AM · $71.0011:25 AM · $71.5811:30 AM · $71.5611:35 AM · $71.6311:40 AM · $71.3411:45 AM · $71.6811:50 AM · $71.7211:55 AM · $72.0812:00 PM · $71.8112:05 PM · $71.7212:10 PM · $71.7412:15 PM · $71.8612:20 PM · $71.8012:25 PM · $71.8112:30 PM · $71.6912:35 PM · $71.9212:40 PM · $71.7012:45 PM · $71.7112:50 PM · $71.6312:55 PM · $71.661:00 PM · $71.531:05 PM · $71.711:10 PM · $71.411:15 PM · $71.271:20 PM · $71.411:25 PM · $71.641:30 PM · $71.421:35 PM · $71.211:40 PM · $71.291:45 PM · $71.341:50 PM · $71.301:55 PM · $71.262:00 PM · $71.032:05 PM · $71.092:10 PM · $70.952:15 PM · $71.102:20 PM · $71.052:25 PM · $70.832:30 PM · $70.702:35 PM · $70.562:40 PM · $70.482:45 PM · $70.462:50 PM · $70.282:55 PM · $70.253:00 PM · $70.193:05 PM · $70.223:10 PM · $70.263:15 PM · $70.333:20 PM · $70.103:25 PM · $70.043:30 PM · $70.053:35 PM · $69.943:40 PM · $69.803:45 PM · $69.943:50 PM · $69.693:55 PM · $69.344:00 PM · $69.39
AI sentiment, last 36h · averaged over 14 stories · 59/100 bullish
AI sentiment 59/100 (bullish)0 · bearish50bullish · 100

The headlines behind the move

Story flow · 8 stories on the wire, last 36h · hover or tap a dot for the headline
36h ago24h ago12h agopublishSeeking Alpha · sentiment 50 · Exelixis, Inc. (EXEL) Q3 2026 Earnings Call TranscriptSeeking Alpha · 50Exelixis, Inc. (EXEL) Q3 2026 Earnings Call TranscriptSeeking Alpha · sentiment 63 · Exelixis outlines March 3, 2027 PDUFA for zanza while advancing Wave 2 pivotal plansSeeking Alpha · 63Exelixis outlines March 3, 2027 PDUFA for zanza while advancing Wave 2 pivotal plansGuruFocus · sentiment 71 · Exelixis (EXEL) Posts Strong Q3 2026 Results, Highlights Growth PipelineGuruFocus · 71Exelixis (EXEL) Posts Strong Q3 2026 Results, Highlights Growth PipelineInvesting.com Analyst Ratings · sentiment 64 · BMO raises Exelixis stock price target to $60 on OpEx outlookInvesting.com Analyst Ratings · 64BMO raises Exelixis stock price target to $60 on OpEx outlookThe Fly · sentiment 63 · Exelixis Price Target Raised To 54 From 49 At BarclaysThe Fly · 63Exelixis Price Target Raised To 54 From 49 At BarclaysGuruFocus · sentiment 64 · Exelixis Inc (EXEL) (Q3 2026) Earnings Call Highlights: CABOMETYX Momentum and Zanzalintinib Pipeline ProgressGuruFocus · 64Exelixis Inc (EXEL) (Q3 2026) Earnings Call Highlights: CABOMETYX Momentum and Zanzalinti…The Fly · sentiment 67 · Exelixis price target raised to $76 from $55 at TD CowenThe Fly · 67Exelixis price target raised to $76 from $55 at TD CowenThe Motley Fool · sentiment 63 · Exelixis (EXEL) Q3 2026 Earnings Call TranscriptThe Motley Fool · 63Exelixis (EXEL) Q3 2026 Earnings Call Transcript
5h agoThe Motley FoolBULLISH 63Earnings

Exelixis (EXEL) Q3 2026 Earnings Call Transcript

Cabozantinib sales grew 11% year over year as zanzalintinib advances toward FDA decisions.

7h agoThe FlyBULLISH 67Analyst

Exelixis price target raised to $76 from $55 at TD Cowen

10h agoGuruFocusBULLISH 64Earnings

Exelixis Inc (EXEL) (Q3 2026) Earnings Call Highlights: CABOMETYX Momentum and Zanzalintinib Pipeline Progress

10h agoThe FlyBULLISH 63Analyst

Exelixis Price Target Raised To 54 From 49 At Barclays

10h agoInvesting.com Analyst RatingsBULLISH 64Analyst

BMO raises Exelixis stock price target to $60 on OpEx outlook

BMO raises Exelixis stock price target to $60 on OpEx outlook

19h agoGuruFocusBULLISH 71Earnings

Exelixis (EXEL) Posts Strong Q3 2026 Results, Highlights Growth Pipeline

19h agoSeeking AlphaBULLISH 63Earnings

Exelixis outlines March 3, 2027 PDUFA for zanza while advancing Wave 2 pivotal plans

Exelixis Q3 2026 earnings: CABOMETYX growth, zanzalintinib pipeline milestones, and key 2027 catalysts.

19h agoSeeking AlphaNEUTRAL 50Earnings

Exelixis, Inc. (EXEL) Q3 2026 Earnings Call Transcript

Exelixis, Inc. (EXEL) Q3 2026 Earnings Call October 29, 2026 5:00 PM EDTCompany ParticipantsAndrew Peters - Senior Vice President of StrategyMichael...

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More on EXEL: full news and sentiment history. Sentiment scores are AI-derived research signals, not financial advice.

Earlier EXEL move explainers: 2026-10-30