TOP TIERMARKET NEWSWIRE
Movers explained · 2026-09-09

Archived explainer. For the current picture see today's BEAM page.

Why Is BEAM THERAPEUTICS IN (BEAM) Stock Down Today?

By the Top Tier Newswire AI Desk · September 9, 2026 at 12:25 AM ET · reviewed against 7 wire stories

BEAM THERAPEUTICS IN (BEAM) is down -9.54% in the latest session. Our newswire has captured 7 stories on BEAM across 4 sources in the last 36 hours, with AI sentiment reading mixed (avg 49/100).

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BEAM stock fell 9.54% to $26.83 on September 8, driven by updated clinical data from its Phase 1/2 trial for BEAM-302, a gene-editing therapy for alpha-1 antitrypsin deficiency. The data, presented at the European Respiratory Society Congress 2026, failed to meet expectations, prompting the company to adjust its regulatory strategy. Beam Therapeutics announced it will pursue an accelerated approval pathway and add 50 more patients to its trial.

What Happened

Beam Therapeutics released updated results for BEAM-302, its one-time gene-editing treatment for AATD, showing AAT protein production under normal physiological control. However, the data did not meet the expectations of investors or analysts, leading to a sharp decline in the stock. The company announced it will seek accelerated approval from the FDA and enroll additional patients to support a future biologics license application. This shift in strategy signals a longer path to commercialization than previously anticipated.

The stock has been volatile in recent weeks, with insiders including CEO John M. Evans and Chief Medical Officer Simon Amy selling shares. The CMO sold on both June 30 and July 27, while the CEO sold on June 29. The most recent insider sale was reported on July 29. Over the past 8 sessions, the stock has declined 11.7% from $30.48 to $26.90.

What The Data Shows

The stock has a market cap of $3.0B and is currently unprofitable, with a trailing twelve-month EPS of -0.84 and a net margin of -55.4%. Revenue grew by 158.9% in the TTM period. The stock traded within a 52-week range of $17.74 to $38.26. On September 8, it printed two fresh 52-week lows and one fresh 52-week high. Volume was unusually high, though specific figures are not provided. The stock’s beta of 2.23 indicates strong volatility relative to the broader market.

What To Watch

Beam Therapeutics is scheduled to present further updates on BEAM-302 in the coming weeks. Investors will also monitor the company’s progress toward its accelerated approval pathway and any changes in coverage from analysts.

AI-assisted analysis composed exclusively from headlines and data on the Top Tier newswire. Public view is delayed 4 hours from real time. Not financial advice.

BEAM by the numbers

Last: $26.83Session: -9.54%7 sessions: -13.98%Coverage: 7 stories / 4 sourcesAI sentiment: 49/100 (mixed)Mkt cap: $3.0B52w: $17.74 to $38.26
BEAM · Sep 9 session (5-min) · -5.48% vs prior close · updated 8:58 PM ET
$25.06$26.13$27.19prev close $26.83$25.367:05 AM10:17 AM1:30 PM4:42 PM7:55 PM7:05 AM · $27.087:10 AM · $26.947:20 AM · $26.887:45 AM · $26.857:50 AM · $26.957:55 AM · $26.958:00 AM · $26.908:05 AM · $26.988:10 AM · $26.888:20 AM · $26.778:30 AM · $26.779:05 AM · $27.009:15 AM · $26.909:25 AM · $26.909:30 AM · $25.909:35 AM · $25.719:40 AM · $25.799:45 AM · $26.119:50 AM · $26.179:55 AM · $26.0410:00 AM · $26.1010:05 AM · $26.1210:10 AM · $26.1110:15 AM · $25.8210:20 AM · $25.8810:25 AM · $25.9410:30 AM · $25.7510:35 AM · $25.6210:40 AM · $25.4610:45 AM · $25.6310:50 AM · $25.5810:55 AM · $25.5711:00 AM · $25.3911:05 AM · $25.5511:10 AM · $25.5711:15 AM · $25.5711:20 AM · $25.4711:25 AM · $25.4211:30 AM · $25.4511:35 AM · $25.4311:40 AM · $25.4411:45 AM · $25.4711:50 AM · $25.3511:55 AM · $25.1812:00 PM · $25.2712:05 PM · $25.2112:10 PM · $25.1812:15 PM · $25.2312:20 PM · $25.2312:25 PM · $25.2512:30 PM · $25.2512:35 PM · $25.2312:40 PM · $25.2412:45 PM · $25.2612:50 PM · $25.2512:55 PM · $25.331:00 PM · $25.271:05 PM · $25.281:10 PM · $25.231:15 PM · $25.201:20 PM · $25.271:25 PM · $25.591:30 PM · $25.561:35 PM · $25.641:40 PM · $25.831:45 PM · $25.791:50 PM · $25.751:55 PM · $25.752:00 PM · $25.822:05 PM · $25.752:10 PM · $25.752:15 PM · $25.682:20 PM · $25.602:25 PM · $25.572:30 PM · $25.552:35 PM · $25.572:40 PM · $25.462:45 PM · $25.522:50 PM · $25.492:55 PM · $25.583:00 PM · $25.553:05 PM · $25.583:10 PM · $25.693:15 PM · $25.693:20 PM · $25.703:25 PM · $25.663:30 PM · $25.633:35 PM · $25.403:40 PM · $25.393:45 PM · $25.343:50 PM · $25.383:55 PM · $25.174:00 PM · $25.664:05 PM · $25.664:20 PM · $25.324:35 PM · $25.345:20 PM · $25.505:35 PM · $25.415:55 PM · $25.366:10 PM · $25.356:25 PM · $25.366:55 PM · $25.457:05 PM · $25.407:10 PM · $25.387:15 PM · $25.357:20 PM · $25.307:30 PM · $25.257:40 PM · $25.247:55 PM · $25.36
AI sentiment, last 36h · averaged over 7 stories · 49/100 neutral
AI sentiment 49/100 (neutral)0 · bearish50bullish · 100

The headlines behind the move

Story flow · 7 stories on the wire, last 36h · hover or tap a dot for the headline
36h ago24h ago12h agopublishBusiness Insider · sentiment 67 · Beam Therapeutics Presents Updated Clinical Data from the Phase 1/2 Trial of BEAM-302 in Alpha-1 Antitrypsin Deficiency (AATD) at the European Respiratory Society (ERS) Congress 2026Business Insider · 67Beam Therapeutics Presents Updated Clinical Data from the Phase 1/2 Trial of BEAM-302 in …The Fly · sentiment 67 · Beam Therapeutics’ BEAM-302 shows efficacy in Phase 1/2 AATD trialThe Fly · 67Beam Therapeutics’ BEAM-302 shows efficacy in Phase 1/2 AATD trialThe Fly · sentiment 38 · Beam Therapeutics falls -12.7%The Fly · 38Beam Therapeutics falls -12.7%The Fly · sentiment 38 · Beam Therapeutics falls -12.4%The Fly · 38Beam Therapeutics falls -12.4%Seeking Alpha · sentiment 59 · Beam Therapeutics Inc. (BEAM) Discusses Updated Phase 1/2 Data for BEAM-302 in Alpha-1 Antitrypsin Deficiency TranscriptSeeking Alpha · 59Beam Therapeutics Inc. (BEAM) Discusses Updated Phase 1/2 Data for BEAM-302 in Alpha-1 An…Business Insider · sentiment 38 · Beam drops after updating Phase 1/2 trial data for gene-editing drugBusiness Insider · 38Beam drops after updating Phase 1/2 trial data for gene-editing drugMorningstar · sentiment 34 · Shares of Beam Therapeutics Retreat After Updated Trial Data DisappointsMorningstar · 34Shares of Beam Therapeutics Retreat After Updated Trial Data Disappoints
4d agoMorningstarBEARISH 34General

Shares of Beam Therapeutics Retreat After Updated Trial Data Disappoints

Based on the feedback from the Food and Drug Administration, Beam plans to pursue an accelerated approval pathway for the treatment. Beam plans to enroll 50 additional patients to support a future biologics license application, the company said.

4d agoBusiness InsiderBEARISH 38Earnings

Beam drops after updating Phase 1/2 trial data for gene-editing drug

Beam Therapeutics (BEAM) stock slips on updated data from a Phase 1/2 trial for BEAM-302, its gene-editing drug for alpha-1 antitrypsin deficiency. Read more here.

4d agoSeeking AlphaBULLISH 59Product/PR

Beam Therapeutics Inc. (BEAM) Discusses Updated Phase 1/2 Data for BEAM-302 in Alpha-1 Antitrypsin Deficiency Transcript

Beam Therapeutics Inc. (BEAM) Discusses Updated Phase 1/2 Data for BEAM-302 in Alpha-1 Antitrypsin Deficiency September 8, 2026 7:00 AM EDTCompany...

4d agoThe FlyBEARISH 38General

Beam Therapeutics falls -12.4%

4d agoThe FlyBEARISH 38General

Beam Therapeutics falls -12.7%

5d agoThe FlyBULLISH 67Product/PR

Beam Therapeutics’ BEAM-302 shows efficacy in Phase 1/2 AATD trial

5d agoBusiness InsiderBULLISH 67Product/PR

Beam Therapeutics Presents Updated Clinical Data from the Phase 1/2 Trial of BEAM-302 in Alpha-1 Antitrypsin Deficiency (AATD) at the European Respiratory Society (ERS) Congress 2026

BEAM-302 Continues to Demonstrate Potential as One-time Treatment for Both Lung and Liver Manifestations of AATD, with AAT Protein Production Under Normal Physiological Control With Up to 18 Months...

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More on BEAM: full news and sentiment history. Sentiment scores are AI-derived research signals, not financial advice.

Earlier BEAM move explainers: 2026-09-09 · 2026-09-08 · 2026-08-26 · 2026-08-25 · 2026-08-20