TOP TIERMARKET NEWSWIRE
Movers explained · 2026-11-13

Archived explainer. For the current picture see today's ANAB page.

Why Is ANAPTYSBIO INC (ANAB) Stock Down Today?

By the Top Tier Newswire AI Desk · November 13, 2026 at 9:50 AM ET · reviewed against 4 wire stories

ANAPTYSBIO INC (ANAB) is down -6.11% in the latest session. Our newswire has captured 4 stories on ANAB across 4 sources in the last 36 hours, with AI sentiment reading bearish (avg 35/100).

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AnaptysBio (ANAB) shares fell 6.11% to $44.85, driven by a quarterly earnings report that missed consensus estimates on both revenue and earnings per share. The company disclosed that first-quarter revenue declined 60.3% year over year to $30.27 million, falling short of analyst expectations by $3.19 million.

What Happened

AnaptysBio filed a Form 8-K on November 12, 2026, to report its fiscal first-quarter 2027 financial results. The company reported GAAP earnings per share of $0.11, which missed the consensus estimate of $0.39 by $0.28. Revenue of $30.27 million also came in below the $33.186 million estimate. The stock had been relatively stable over the previous eight sessions, moving just 0.1% from $47.73 to $47.77, before the gap-down opening.

What The Data Shows

The stock opened at $45.01, a 5.8% gap down from the prior close of $47.77. Intraday trading saw a session high of $46.51 at 8:25 AM ET and a session low of $44.64 at 9:45 AM ET. Volume so far stands at 0.0M shares, which is 0.1 times the three-month daily average. Fundamentally, the company has a market capitalization of $1.5 billion and a P/E ratio of 5.1. Trailing twelve-month revenue has grown 107.7%, and the net margin is 247.0%. The stock has a beta of 0.37 and a 52-week range of $32.90 to $73.30. On November 13, 2026, the stock printed three fresh 52-week lows. Recent insider activity includes a sale by director Renton Hollings on October 1, 2026. Over the last 90 days, there have been zero buys and one sell totaling $249,000.

What To Watch

AnaptysBio has announced participation in upcoming investor conferences. The stock's recent deterioration in sentiment, with a seven-day average lower than the 30-day average, suggests continued volatility as the market digests the earnings miss and litigation challenges.

AI-assisted analysis composed exclusively from headlines and data on the Top Tier newswire. Public view is delayed 4 hours from real time. Not financial advice.

ANAB by the numbers

Last: $44.85Session: -6.11%7 sessions: -2.65%Coverage: 4 stories / 4 sourcesAI sentiment: 35/100 (bearish)Mkt cap: $1.5BP/E: 5.152w: $32.90 to $73.30
ANAB · Nov 13 session (5-min) · -3.18% vs prior close · updated 8:54 PM ET
$44.45$46.21$47.96prev close $47.77$46.258:15 AM10:11 AM12:07 PM2:03 PM4:00 PM8:15 AM · $45.398:20 AM · $45.418:25 AM · $46.518:30 AM · $45.998:35 AM · $46.218:40 AM · $46.208:50 AM · $46.209:30 AM · $45.919:35 AM · $45.919:40 AM · $45.019:45 AM · $44.649:50 AM · $44.909:55 AM · $45.6410:00 AM · $46.0510:05 AM · $46.0610:10 AM · $46.0710:15 AM · $46.3810:20 AM · $46.4510:25 AM · $46.6610:30 AM · $47.1010:35 AM · $47.1310:40 AM · $46.8210:45 AM · $47.1610:50 AM · $46.8910:55 AM · $46.6011:00 AM · $46.4611:05 AM · $46.3511:10 AM · $46.4811:15 AM · $46.4211:20 AM · $46.5511:25 AM · $46.7211:30 AM · $46.9811:35 AM · $46.8511:40 AM · $46.7611:45 AM · $46.7511:50 AM · $46.9711:55 AM · $47.0512:00 PM · $46.7112:05 PM · $46.8212:10 PM · $46.7312:15 PM · $46.7412:20 PM · $46.7212:25 PM · $46.6212:30 PM · $46.3412:35 PM · $46.2112:40 PM · $46.2012:45 PM · $46.1412:50 PM · $46.3012:55 PM · $46.241:00 PM · $46.261:05 PM · $46.311:10 PM · $46.301:20 PM · $46.421:25 PM · $46.421:30 PM · $46.601:35 PM · $46.451:40 PM · $46.481:45 PM · $46.371:50 PM · $46.401:55 PM · $46.352:00 PM · $46.492:05 PM · $46.502:10 PM · $46.472:15 PM · $46.452:25 PM · $46.332:30 PM · $46.332:35 PM · $46.452:40 PM · $46.402:45 PM · $46.412:50 PM · $46.352:55 PM · $46.283:00 PM · $46.293:05 PM · $46.523:10 PM · $46.633:15 PM · $46.563:20 PM · $46.583:25 PM · $46.443:30 PM · $46.283:35 PM · $46.193:40 PM · $46.303:45 PM · $46.383:50 PM · $46.283:55 PM · $46.274:00 PM · $46.25
AI sentiment, last 36h · averaged over 4 stories · 35/100 bearish
AI sentiment 35/100 (bearish)0 · bearish50bullish · 100

The headlines behind the move

Story flow · 4 stories on the wire, last 36h · hover or tap a dot for the headline
36h ago24h ago12h agopublishSEC 8-K · sentiment 50 · ANAPTYSBIO, INC (ANAB) files 8-K: Items 2.02, 9.01SEC 8-K · 50ANAPTYSBIO, INC (ANAB) files 8-K: Items 2.02, 9.01The Fly · sentiment 22 · AnaptysBio reports Q1 EPS 11c, consensus 39cThe Fly · 22AnaptysBio reports Q1 EPS 11c, consensus 39cSeeking Alpha · sentiment 34 · AnaptysBio GAAP EPS of $0.11 misses by $0.28, revenue of $30.27M misses by $3.19MSeeking Alpha · 34AnaptysBio GAAP EPS of $0.11 misses by $0.28, revenue of $30.27M misses by $3.19MGuruFocus · sentiment 34 · AnaptysBio (ANAB) Q1 Earnings Miss Amid Litigation ChallengesGuruFocus · 34AnaptysBio (ANAB) Q1 Earnings Miss Amid Litigation Challenges
1d agoGuruFocusBEARISH 34Earnings

AnaptysBio (ANAB) Q1 Earnings Miss Amid Litigation Challenges

1d agoSeeking AlphaBEARISH 34Earnings

AnaptysBio GAAP EPS of $0.11 misses by $0.28, revenue of $30.27M misses by $3.19M

AnaptysBio Q1 GAAP EPS is $0.11, missing estimates by $0.28; revenue falls 60.3% year over year to $30.27M, $3.19M below estimates.

1d agoThe FlyBEARISH 22Earnings

AnaptysBio reports Q1 EPS 11c, consensus 39c

1d agoSEC 8-KNEUTRAL 50General

ANAPTYSBIO, INC (ANAB) files 8-K: Items 2.02, 9.01

Filed: 2026-11-12 AccNo: 0001193125-26-458461 Size: 423 KB Item 2.02: Results of Operations and Financial Condition Item 9.01: Financial Statements and Exhibits

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More on ANAB: full news and sentiment history. Sentiment scores are AI-derived research signals, not financial advice.

Earlier ANAB move explainers: 2026-11-13 · 2026-09-22