TOP TIERMARKET NEWSWIRE
Movers explained · 2026-09-08

Archived explainer. For the current picture see today's AMGN page.

Why Is AMGEN INC (AMGN) Stock Down Today?

By the Top Tier Newswire AI Desk · September 8, 2026 at 10:30 AM ET · reviewed against 14 wire stories

AMGEN INC (AMGN) is down -9.21% in the latest session. Our newswire has captured 14 stories on AMGN across 9 sources in the last 36 hours, with AI sentiment reading mixed (avg 48/100).

Public view, delayed 4h. Every headline, price and sentiment read below — and this write-up itself — reaches Pro subscribers live. Public readers see it once it clears the delay.

AMGN stock fell 9.21% to $396.97 on Tuesday, marking one of the largest single-session declines in recent months. The drop came amid a broader market reaction to Novartis’ disappointing drug trial results and a shift in risk-reward dynamics for biotech stocks. The stock opened with a -4.9% gap from the previous close and continued to fall throughout the session, reaching a low of $396.89 before stabilizing slightly in the final minutes.

What Happened

The decline was driven by a combination of sector-wide concerns and specific developments affecting Amgen. A key factor was the broader market reaction to Novartis’ recent drug trial results, which caused a ripple effect across biotech names. Amgen itself reported positive Phase 3 DeLLphi-305 study results for its drug combination in treating small cell lung cancer, but the news came after the market had already turned bearish. Analysts from BMO downgraded Amgen to Market Perform, citing a shift in risk-reward dynamics, while Cantor Fitzgerald reiterated a Neutral stance with a $400 price target. Additionally, recent insider sales by senior executives and a lack of strong follow-through from recent trial announcements contributed to the selling pressure.

What The Data Shows

The intraday session showed a sharp decline from the open, with volume reaching 1.2 million shares, or 0.4 times the 3-month average. The stock is currently trading near its 52-week low of $269.77, having fallen from a high of $447.03 earlier in the year. Over the last 8 sessions, the stock has declined 0.7% to $437.32. Recent insider transactions include three sales totaling $4.1 million, with the most recent filing on August 13. The 52-week tape also showed one fresh 52-week high and 10 fresh 52-week lows on September 8. The stock’s beta of 0.43 suggests it is less volatile than the broader market, but recent sentiment has deteriorated, with a 7-day average of 49/100 compared to a 30-day average of 56/100.

What To Watch

Investors should monitor the company’s next earnings report, which is not currently scheduled. In the near term, the focus will be on analyst coverage and how the market reacts to the latest trial results and broader biotech sector dynamics.

AI-assisted analysis composed exclusively from headlines and data on the Top Tier newswire. Public view is delayed 4 hours from real time. Not financial advice.

AMGN by the numbers

Last: $396.97Session: -9.21%7 sessions: -10.10%Coverage: 14 stories / 9 sourcesAI sentiment: 48/100 (mixed)Mkt cap: $236.4BP/E: 27.252w: $269.77 to $447.03
AMGN · Sep 8 session (5-min) · -9.97% vs prior close · updated 9:00 PM ET
$389$415$440prev close $437.23$393.647:00 AM10:13 AM1:27 PM4:41 PM7:55 PM7:00 AM · $415.837:05 AM · $415.257:10 AM · $415.007:15 AM · $415.007:20 AM · $413.087:25 AM · $412.007:30 AM · $412.397:35 AM · $412.357:40 AM · $410.207:45 AM · $410.257:50 AM · $410.007:55 AM · $411.018:00 AM · $412.008:05 AM · $411.008:10 AM · $411.008:15 AM · $411.008:20 AM · $411.008:25 AM · $411.108:30 AM · $411.008:35 AM · $411.508:40 AM · $411.508:45 AM · $411.508:50 AM · $412.008:55 AM · $412.509:00 AM · $412.009:05 AM · $412.009:10 AM · $411.709:15 AM · $411.259:20 AM · $412.009:25 AM · $408.919:30 AM · $403.289:35 AM · $406.069:40 AM · $407.119:45 AM · $405.999:50 AM · $405.899:55 AM · $403.4210:00 AM · $402.0810:05 AM · $401.7610:10 AM · $400.9910:15 AM · $399.5510:20 AM · $398.6110:25 AM · $397.3310:30 AM · $396.9010:35 AM · $396.2010:40 AM · $398.1710:45 AM · $397.6610:50 AM · $397.9110:55 AM · $397.0011:00 AM · $397.7611:05 AM · $397.4411:10 AM · $395.9011:15 AM · $396.5811:20 AM · $396.6611:25 AM · $396.0711:30 AM · $395.7811:35 AM · $395.4511:40 AM · $394.9811:45 AM · $396.0211:50 AM · $394.7511:55 AM · $395.1212:00 PM · $395.0212:05 PM · $394.5512:10 PM · $394.3212:15 PM · $394.0512:20 PM · $395.4412:25 PM · $395.6912:30 PM · $394.0012:35 PM · $392.8012:40 PM · $392.0812:45 PM · $393.7812:50 PM · $394.3812:55 PM · $394.541:00 PM · $393.691:05 PM · $394.721:10 PM · $394.971:15 PM · $395.831:20 PM · $396.891:25 PM · $398.381:30 PM · $396.961:35 PM · $396.221:40 PM · $397.301:45 PM · $397.931:50 PM · $398.251:55 PM · $398.042:00 PM · $397.512:05 PM · $398.102:10 PM · $397.112:15 PM · $395.482:20 PM · $395.622:25 PM · $395.742:30 PM · $394.802:35 PM · $394.792:40 PM · $395.682:45 PM · $395.162:50 PM · $395.062:55 PM · $395.563:00 PM · $395.543:05 PM · $396.673:10 PM · $395.993:15 PM · $394.993:20 PM · $393.913:25 PM · $394.213:30 PM · $394.373:35 PM · $394.593:40 PM · $394.183:45 PM · $392.633:50 PM · $391.833:55 PM · $393.234:00 PM · $393.094:05 PM · $393.174:10 PM · $393.174:15 PM · $393.124:20 PM · $393.104:25 PM · $393.334:30 PM · $393.904:35 PM · $393.804:45 PM · $393.404:50 PM · $393.064:55 PM · $393.775:00 PM · $393.675:05 PM · $393.715:20 PM · $393.175:25 PM · $393.725:30 PM · $393.175:40 PM · $393.605:45 PM · $393.626:05 PM · $393.486:10 PM · $393.366:20 PM · $393.136:30 PM · $393.506:35 PM · $393.386:40 PM · $393.446:55 PM · $393.467:05 PM · $393.547:10 PM · $393.657:15 PM · $393.647:20 PM · $393.657:25 PM · $393.677:35 PM · $393.597:40 PM · $393.507:45 PM · $393.527:55 PM · $393.64
AI sentiment, last 36h · averaged over 14 stories · 48/100 neutral
AI sentiment 48/100 (neutral)0 · bearish50bullish · 100

The headlines behind the move

Story flow · 8 stories on the wire, last 36h · hover or tap a dot for the headline
36h ago24h ago12h agopublishInvesting.com Markets · sentiment 46 · BMO lowers Amgen, BioNTech to Market Perform as risk-reward shiftsInvesting.com Markets · 46BMO lowers Amgen, BioNTech to Market Perform as risk-reward shiftsBarron's · sentiment 53 · Intel, Amgen, Novartis, Bloom Energy, and More Stocks That Explain Today’s MarketBarron's · 53Intel, Amgen, Novartis, Bloom Energy, and More Stocks That Explain Today’s MarketBarron's · sentiment 32 · Why Novartis’ Drug Trial Results Are Blowing Up Amgen StockBarron's · 32Why Novartis’ Drug Trial Results Are Blowing Up Amgen StockYahoo Finance · sentiment 50 · Here Are Tuesday’s Top Wall Street Analyst Research Calls: Amgen, Baidu, Best Buy, Circle Internet, Corning, Intel, Lockheed Martin SpaceX, TeraWulf and MoreYahoo Finance · 50Here Are Tuesday’s Top Wall Street Analyst Research Calls: Amgen, Baidu, Best Buy, Circle…PR Newswire · sentiment 78 · IMDELLTRA® IN COMBINATION WITH IMFINZI® DEMONSTRATED LANDMARK IMPROVEMENT IN OVERALL SURVIVAL IN FIRST-LINE EXTENSIVE STAGE SMALL CELL LUNG CANCERPR Newswire · 78IMDELLTRA® IN COMBINATION WITH IMFINZI® DEMONSTRATED LANDMARK IMPROVEMENT IN OVERALL SURV…The Fly · sentiment 67 · Amgen, AstraZeneca report Phase 3 DeLLphi-305 study met primary endpointThe Fly · 67Amgen, AstraZeneca report Phase 3 DeLLphi-305 study met primary endpointTrading Economics · sentiment 38 · Amgen Stock Price Hits 4-week LowTrading Economics · 38Amgen Stock Price Hits 4-week LowYahoo Top · sentiment 55 · Stocks to Watch: Amgen, Nike, Rigetti; Bloom EnergyYahoo Top · 55Stocks to Watch: Amgen, Nike, Rigetti; Bloom Energy
4d agoYahoo TopBULLISH 55General

Stocks to Watch: Amgen, Nike, Rigetti; Bloom Energy

4d agoTrading EconomicsBEARISH 38General

Amgen Stock Price Hits 4-week Low

Amgen shares decreased to 407.08 USD, the lowest since August 2026. Over the past 4 weeks, Amgen gained 0.05%, and in the last 12 months, it increased 43.85%.

4d agoThe FlyBULLISH 67Product/PR

Amgen, AstraZeneca report Phase 3 DeLLphi-305 study met primary endpoint

4d agoPR NewswireBULLISH 78Product/PR

IMDELLTRA® IN COMBINATION WITH IMFINZI® DEMONSTRATED LANDMARK IMPROVEMENT IN OVERALL SURVIVAL IN FIRST-LINE EXTENSIVE STAGE SMALL CELL LUNG CANCER

Phase 3 DeLLphi-305 Study Delivered Highly Significant and Clinically Meaningful Overall Survival Benefit Versus Durvalumab Alone Study Also Met Secondary Progression-Free Survival and Objective Response Rate Endpoints THOUSAND OAKS, Calif., Sept. 8, 2026 /PRNewswire/ -- Amgen (NASDAQ:...

5d agoYahoo FinanceNEUTRAL 50Analyst

Here Are Tuesday’s Top Wall Street Analyst Research Calls: Amgen, Baidu, Best Buy, Circle Internet, Corning, Intel, Lockheed Martin SpaceX, TeraWulf and More

5d agoBarron'sBEARISH 32General

Why Novartis’ Drug Trial Results Are Blowing Up Amgen Stock

5d agoBarron'sNEUTRAL 53General

Intel, Amgen, Novartis, Bloom Energy, and More Stocks That Explain Today’s Market

Intel, Marvell, and Sandisk rise despite the market’s inflation worries. Amgen falls following Novartis’ disappointing trial data.

5d agoInvesting.com MarketsNEUTRAL 46Analyst

BMO lowers Amgen, BioNTech to Market Perform as risk-reward shifts

BMO lowers Amgen, BioNTech to Market Perform as risk-reward shifts

Want the next move before the crowd? The live terminal streams every headline in real time with watchlist alerts, AI sentiment, and the full data stack behind this page.Get Pro Access →

More on AMGN: full news and sentiment history. Sentiment scores are AI-derived research signals, not financial advice.

Earlier AMGN move explainers: 2026-09-09 · 2026-09-08 · 2026-08-31