TOP TIERMARKET NEWSWIRE
Movers explained · 2026-09-03

Archived explainer. For the current picture see today's ALMS page.

Why Is ALUMIS INC EQUITY (ALMS) Stock Up Today?

By the Top Tier Newswire AI Desk · September 3, 2026 at 2:47 PM ET · reviewed against 9 wire stories

ALUMIS INC EQUITY (ALMS) is up +14.69% in the latest session. Our newswire has captured 9 stories on ALMS across 3 sources in the last 36 hours, with AI sentiment reading bearish (avg 41/100).

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Why ALMS stock is up today

Alumis Inc (ALMS) shares surged 14.69% to $11.87 in a volatile session that followed a sharp decline in recent weeks. The stock opened lower but reversed sharply in afternoon trading, reaching a session high of $11.89. The rally appears to be driven by a mix of analyst activity and retail interest, as well as a reaction to recent downgrades and price target cuts.

What Happened

Guggenheim downgraded Alumis to Neutral from Buy after a mid-stage trial setback for the company’s systemic lupus erythematosus (SLE) candidate. This followed a similar downgrade from Morgan Stanley, which cut its price target for Alumis after the lupus trial failure. Oppenheimer also lowered its price target to $37 from $55, and Morgan Stanley reduced its target to $29 from $39. Meanwhile, H.C. Wainwright upgraded Alumis to Buy from Neutral, adding to the mixed analyst sentiment. The stock has been under pressure in recent sessions, having fallen 50.6% over the last eight days. The intraday reversal suggests a short-covering or speculative rebound.

What The Data Shows

The stock opened at $10.25, a 1.0% gap down from the prior close, and traded as low as $10.10 before climbing to a high of $11.89. Volume has reached 3.4 million shares, more than double the 3-month daily average. Unusual options activity has also been noted, with $140K in call premium and $135K in put premium traded. The stock is currently trading near the upper end of its 52-week range of $3.76 to $31.35. Recent insider transactions show multiple executives selling shares, with total sales of $534K reported in the last 90 days.

What To Watch

Alumis is not scheduled to report earnings in the near term. Investors should monitor the breadth of analyst coverage and any further updates on the lupus drug development.

AI-assisted analysis composed exclusively from headlines and data on the Top Tier newswire. Public view is delayed 4 hours from real time. Not financial advice.

ALMS by the numbers

Last: $11.87Session: +14.69%7 sessions: -52.48%Coverage: 9 stories / 3 sourcesAI sentiment: 41/100 (bearish)Mkt cap: $1.2B52w: $3.76 to $31.35
ALMS · Sep 3 session (5-min) · +9.86% vs prior close · updated 8:52 PM ET
$10.04$11.00$11.97prev close $10.35$11.377:00 AM10:13 AM1:27 PM4:41 PM7:55 PM7:00 AM · $10.227:05 AM · $10.147:10 AM · $10.257:15 AM · $10.307:20 AM · $10.307:25 AM · $10.307:30 AM · $10.397:35 AM · $10.407:40 AM · $10.397:45 AM · $10.397:50 AM · $10.407:55 AM · $10.408:00 AM · $10.388:05 AM · $10.408:20 AM · $10.258:25 AM · $10.278:35 AM · $10.408:40 AM · $10.398:50 AM · $10.448:55 AM · $10.449:05 AM · $10.449:10 AM · $10.459:20 AM · $10.449:25 AM · $10.359:30 AM · $10.709:35 AM · $10.719:40 AM · $10.899:45 AM · $10.729:50 AM · $10.859:55 AM · $10.8510:00 AM · $10.8510:05 AM · $11.0010:10 AM · $11.0710:15 AM · $11.2210:20 AM · $11.1510:25 AM · $11.2010:30 AM · $11.0910:35 AM · $11.1810:40 AM · $11.1010:45 AM · $11.2910:50 AM · $11.2710:55 AM · $11.3811:00 AM · $11.3411:05 AM · $11.2911:10 AM · $11.2911:15 AM · $11.2911:20 AM · $11.2811:25 AM · $11.2811:30 AM · $11.2911:35 AM · $11.4311:40 AM · $11.4311:45 AM · $11.3911:50 AM · $11.4011:55 AM · $11.3812:00 PM · $11.3412:05 PM · $11.3112:10 PM · $11.3212:15 PM · $11.3712:20 PM · $11.3412:25 PM · $11.3912:30 PM · $11.3812:35 PM · $11.3012:40 PM · $11.4612:45 PM · $11.3812:50 PM · $11.4012:55 PM · $11.411:00 PM · $11.481:05 PM · $11.451:10 PM · $11.401:15 PM · $11.461:20 PM · $11.481:25 PM · $11.471:30 PM · $11.491:35 PM · $11.501:40 PM · $11.531:45 PM · $11.541:50 PM · $11.571:55 PM · $11.642:00 PM · $11.622:05 PM · $11.722:10 PM · $11.702:15 PM · $11.682:20 PM · $11.682:25 PM · $11.672:30 PM · $11.722:35 PM · $11.762:40 PM · $11.782:45 PM · $11.872:50 PM · $11.872:55 PM · $11.773:00 PM · $11.753:05 PM · $11.553:10 PM · $11.543:15 PM · $11.623:20 PM · $11.553:25 PM · $11.583:30 PM · $11.593:35 PM · $11.383:40 PM · $11.273:45 PM · $11.263:50 PM · $11.153:55 PM · $11.354:00 PM · $11.364:05 PM · $11.404:10 PM · $11.354:30 PM · $11.364:35 PM · $11.364:50 PM · $11.434:55 PM · $11.366:40 PM · $11.366:50 PM · $11.496:55 PM · $11.367:10 PM · $11.387:45 PM · $11.327:55 PM · $11.37
AI sentiment, last 36h · averaged over 9 stories · 41/100 bearish
AI sentiment 41/100 (bearish)0 · bearish50bullish · 100

The headlines behind the move

Story flow · 8 stories on the wire, last 36h · hover or tap a dot for the headline
36h ago24h ago12h agopublishThe Fly · sentiment 61 · Alumis upgraded to Buy from Neutral at H.C. WainwrightThe Fly · 61Alumis upgraded to Buy from Neutral at H.C. WainwrightThe Fly · sentiment 34 · Alumis price target lowered to $29 from $39 at Morgan StanleyThe Fly · 34Alumis price target lowered to $29 from $39 at Morgan StanleyInvesting.com Analyst Ratings · sentiment 28 · Morgan Stanley cuts Alumis stock price target on lupus trial failureInvesting.com Analyst Ratings · 28Morgan Stanley cuts Alumis stock price target on lupus trial failureThe Fly · sentiment 34 · Alumis price target lowered to $37 from $55 at OppenheimerThe Fly · 34Alumis price target lowered to $37 from $55 at OppenheimerThe Fly · sentiment 58 · Alumis rises 10.7%The Fly · 58Alumis rises 10.7%Investing.com Analyst Ratings · sentiment 32 · Guggenheim downgrades Alumis stock rating after trial missInvesting.com Analyst Ratings · 32Guggenheim downgrades Alumis stock rating after trial missThe Fly · sentiment 48 · Alumis downgraded to Neutral from Buy at GuggenheimThe Fly · 48Alumis downgraded to Neutral from Buy at GuggenheimSeeking Alpha · sentiment 32 · Alumis downgraded at Guggenheim after trial setback for SLE candidateSeeking Alpha · 32Alumis downgraded at Guggenheim after trial setback for SLE candidate
10d agoSeeking AlphaBEARISH 32Analyst

Alumis downgraded at Guggenheim after trial setback for SLE candidate

Alumis (ALMS) stock was downgraded at Guggenheim after a mid-stage trial setback for the company

10d agoThe FlyNEUTRAL 48Analyst

Alumis downgraded to Neutral from Buy at Guggenheim

10d agoInvesting.com Analyst RatingsBEARISH 32Analyst

Guggenheim downgrades Alumis stock rating after trial miss

Guggenheim downgrades Alumis stock rating after trial miss

10d agoThe FlyBULLISH 58General

Alumis rises 10.7%

11d agoThe FlyBEARISH 34Analyst

Alumis price target lowered to $37 from $55 at Oppenheimer

11d agoInvesting.com Analyst RatingsBEARISH 28Analyst

Morgan Stanley cuts Alumis stock price target on lupus trial failure

Morgan Stanley cuts Alumis stock price target on lupus trial failure

11d agoThe FlyBEARISH 34Analyst

Alumis price target lowered to $29 from $39 at Morgan Stanley

11d agoThe FlyBULLISH 61Analyst

Alumis upgraded to Buy from Neutral at H.C. Wainwright

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More on ALMS: full news and sentiment history. Sentiment scores are AI-derived research signals, not financial advice.

Earlier ALMS move explainers: 2026-09-03 · 2026-09-02 · 2026-09-01