By the Top Tier Newswire AI Desk · September 3, 2026 at 2:47 PM ET · reviewed against 9 wire stories
ALUMIS INC EQUITY (ALMS) is up +14.69% in the latest session. Our newswire has captured 9 stories on ALMS across 3 sources in the last 36 hours, with AI sentiment reading bearish (avg 41/100).
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Why ALMS stock is up today
Alumis Inc (ALMS) shares surged 14.69% to $11.87 in a volatile session that followed a sharp decline in recent weeks. The stock opened lower but reversed sharply in afternoon trading, reaching a session high of $11.89. The rally appears to be driven by a mix of analyst activity and retail interest, as well as a reaction to recent downgrades and price target cuts.
What Happened
Guggenheim downgraded Alumis to Neutral from Buy after a mid-stage trial setback for the company’s systemic lupus erythematosus (SLE) candidate. This followed a similar downgrade from Morgan Stanley, which cut its price target for Alumis after the lupus trial failure. Oppenheimer also lowered its price target to $37 from $55, and Morgan Stanley reduced its target to $29 from $39. Meanwhile, H.C. Wainwright upgraded Alumis to Buy from Neutral, adding to the mixed analyst sentiment. The stock has been under pressure in recent sessions, having fallen 50.6% over the last eight days. The intraday reversal suggests a short-covering or speculative rebound.
What The Data Shows
The stock opened at $10.25, a 1.0% gap down from the prior close, and traded as low as $10.10 before climbing to a high of $11.89. Volume has reached 3.4 million shares, more than double the 3-month daily average. Unusual options activity has also been noted, with $140K in call premium and $135K in put premium traded. The stock is currently trading near the upper end of its 52-week range of $3.76 to $31.35. Recent insider transactions show multiple executives selling shares, with total sales of $534K reported in the last 90 days.
What To Watch
Alumis is not scheduled to report earnings in the near term. Investors should monitor the breadth of analyst coverage and any further updates on the lupus drug development.
AI-assisted analysis composed exclusively from headlines and data on the Top Tier newswire. Public view is delayed 4 hours from real time. Not financial advice.
Morgan Stanley cuts Alumis stock price target on lupus trial failure
Morgan Stanley cuts Alumis stock price target on lupus trial failure
11d agoThe FlyBEARISH 34Analyst
Alumis price target lowered to $29 from $39 at Morgan Stanley
11d agoThe FlyBULLISH 61Analyst
Alumis upgraded to Buy from Neutral at H.C. Wainwright
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