TOP TIERMARKET NEWSWIRE
Movers explained · October 5, 2026

Why Is VAXCYTE INC (PCVX) Stock Up Today?

By the Top Tier Newswire AI Desk · reviewed against 19 wire stories

VAXCYTE INC (PCVX) is up +36.23% in the latest session. Our newswire has captured 19 stories on PCVX across 11 sources in the last 36 hours, with AI sentiment reading bullish (avg 63/100).

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PCVX by the numbers

Last: $76.94Session: +36.23%7 sessions: -0.35%Coverage: 19 stories / 11 sourcesAI sentiment: 63/100 (bullish)
PCVX · today's session (5-min) · +36.08% vs prior close · updated 10:29 AM ET
$54.41$73.74$93.07prev close $56.48$76.867:00 AM7:51 AM8:42 AM9:33 AM10:25 AM7:00 AM · $90.997:05 AM · $87.467:10 AM · $85.237:15 AM · $85.287:20 AM · $85.207:25 AM · $88.507:30 AM · $87.487:35 AM · $85.577:40 AM · $86.027:45 AM · $86.507:50 AM · $87.877:55 AM · $88.258:00 AM · $86.708:05 AM · $85.348:10 AM · $86.288:15 AM · $86.308:20 AM · $87.458:25 AM · $88.648:30 AM · $88.858:35 AM · $88.008:40 AM · $88.708:45 AM · $88.588:50 AM · $88.648:55 AM · $89.009:00 AM · $89.009:05 AM · $89.009:10 AM · $88.889:15 AM · $89.189:20 AM · $88.519:25 AM · $87.009:30 AM · $89.509:35 AM · $87.519:40 AM · $87.999:45 AM · $85.509:50 AM · $83.629:55 AM · $82.7410:00 AM · $79.5510:05 AM · $79.4210:10 AM · $78.6910:15 AM · $77.5510:20 AM · $77.0910:25 AM · $76.86
AI sentiment, last 36h · averaged over 19 stories · 63/100 bullish
AI sentiment 63/100 (bullish)0 · bearish50bullish · 100

The headlines behind the move

Story flow · 10 stories on the wire, last 36h · hover or tap a dot for the headline
36h ago24h ago12h agonowThe Fly · sentiment 61 · Vaxcyte price target raised to $125 from $116 at GuggenheimThe Fly · 61Vaxcyte price target raised to $125 from $116 at GuggenheimBarron's · sentiment 42 · S&P 500 Futures Decline in Premarket Trading; Vaxcyte, PTC LeadBarron's · 42S&P 500 Futures Decline in Premarket Trading; Vaxcyte, PTC LeadSEC 8-K · sentiment 50 · Vaxcyte, Inc. (PCVX) files 8-KSEC 8-K · 50Vaxcyte, Inc. (PCVX) files 8-KInvestorsHub · sentiment 78 · Vaxcyte Shares Rise 50% After VAX-31 Meets Primary Endpoints in Phase 3 TrialInvestorsHub · 78Vaxcyte Shares Rise 50% After VAX-31 Meets Primary Endpoints in Phase 3 TrialInvestors.com · sentiment 67 · Vaxcyte Catapults After Going Toe-To-Toe With Pfizer, Merck In Vaccine StudyInvestors.com · 67Vaxcyte Catapults After Going Toe-To-Toe With Pfizer, Merck In Vaccine StudyThe Fly · sentiment 67 · Vaxcyte can trade in $90-$100 range on data, says MizuhoThe Fly · 67Vaxcyte can trade in $90-$100 range on data, says MizuhoThe Fly · sentiment 32 · Vaxcyte data hit ‘blue-sky’ case, says JefferiesThe Fly · 32Vaxcyte data hit ‘blue-sky’ case, says JefferiesThe Fly · sentiment 64 · Vaxcyte rises 46.4%The Fly · 64Vaxcyte rises 46.4%Barron's · sentiment 73 · Vaxcyte Stock Spikes 57% as Lead Vaccine Candidate Takes Aim at Pfizer and MerckBarron's · 73Vaxcyte Stock Spikes 57% as Lead Vaccine Candidate Takes Aim at Pfizer and MerckMarketChameleon · sentiment 76 · PCVX rallies after OPUS-1 Phase 3 data show VAX-31 hit all primary endpoints and cleared 321 immunobridging comparisonsMarketChameleon · 76PCVX rallies after OPUS-1 Phase 3 data show VAX-31 hit all primary endpoints and cleared …
5m agoMarketChameleonBULLISH 76Product/PR

PCVX rallies after OPUS-1 Phase 3 data show VAX-31 hit all primary endpoints and cleared 321 immunobridging comparisons

Vaxcyte reported positive topline Phase 3 OPUS-1 results for VAX-31, saying the 31-valent pneumococcal vaccine candidate met all prespecified primary endpoints in adults 50+ and achieved noninferiority across all 321 immunobridging comparisons in adults 18–49. The company said safety was similar to PCV20 and PCV21 and reiterated plans to read out OPUS-2 and OPUS-3 in 1H 2027 ahead of a planned BLA submission in 1H 2028.

8m agoBarron'sBULLISH 73Product/PR

Vaxcyte Stock Spikes 57% as Lead Vaccine Candidate Takes Aim at Pfizer and Merck

30m agoThe FlyBULLISH 64General

Vaxcyte rises 46.4%

34m agoThe FlyBEARISH 32General

Vaxcyte data hit ‘blue-sky’ case, says Jefferies

39m agoThe FlyBULLISH 67Analyst

Vaxcyte can trade in $90-$100 range on data, says Mizuho

1h agoInvestors.comBULLISH 67Product/PR

Vaxcyte Catapults After Going Toe-To-Toe With Pfizer, Merck In Vaccine Study

2h agoInvestorsHubBULLISH 78Product/PR

Vaxcyte Shares Rise 50% After VAX-31 Meets Primary Endpoints in Phase 3 Trial

Vaxcyte shares rise 50% after its VAX-31 pneumococcal vaccine candidate met all prespecified primary endpoints in the pivotal OPUS-1 Phase 3 trial.

2h agoSEC 8-KNEUTRAL 50General

Vaxcyte, Inc. (PCVX) files 8-K

Filed: 2026-10-05 AccNo: 0001193125-26-413168 Size: 3 MB Item 7.01: Regulation FD Disclosure Item 8.01: Other Events Item 9.01: Financial Statements and Exhibits

3h agoBarron'sBEARISH 42General

S&P 500 Futures Decline in Premarket Trading; Vaxcyte, PTC Lead

3h agoThe FlyBULLISH 61Analyst

Vaxcyte price target raised to $125 from $116 at Guggenheim

Frequently asked questions

Why is PCVX stock up today?

VAXCYTE INC (PCVX) is up +36.23% in the latest session. Our newswire has captured 19 stories on PCVX across 11 sources in the last 36 hours, with AI sentiment reading bullish (avg 63/100). The most recent driver: "PCVX rallies after OPUS-1 Phase 3 data show VAX-31 hit all primary endpoints and cleared 321 immunobridging comparisons" (MarketChameleon).

Is PCVX a buy right now?

Top Tier Newswire does not give financial advice. Our AI sentiment across the last 36 hours of PCVX coverage reads 63/100 over 19 stories; treat it as a research signal and do your own diligence.

How fast does this page update?

The data sections refresh continuously as the newswire lands coverage; the written analysis is published once per trading day. Pro subscribers additionally get real-time push alerts, watchlists, and the full live terminal.

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More on PCVX: full news and sentiment history. Sentiment scores are AI-derived research signals, not financial advice.