TOP TIERMARKET NEWSWIRE
Movers explained · September 22, 2026

Why Is CELLDEX THERAPEUTICS (CLDX) Stock Down Today?

By the Top Tier Newswire AI Desk · July 16, 2026 at 9:47 AM ET · reviewed against 9 wire stories

CELLDEX THERAPEUTICS (CLDX) is down -13.42% in the latest session. Our newswire has captured 9 stories on CLDX across 8 sources in the last 36 hours, with AI sentiment reading bullish (avg 58/100).

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Celldex Therapeutics (CLDX) fell 6.28% to $35.90 in early trading on Monday driven by the filing of an SEC 8-K disclosing the departure or appointment of certain officers. The document highlighted changes in executive compensation arrangements, which has raised questions among investors about leadership stability and strategic direction.

What Happened

The stock opened at $38.07, a modest 0.6% gap down from the prior close, but quickly declined to a session low of $35.67 within 15 minutes of the open. The SEC filing, dated July 15, included details about the departure of directors or certain officers and related compensatory arrangements. While the filing itself does not specify the names of those involved, it is likely linked to the broader context of Celldex's leadership changes. Separately, Benzinga reported that CFO Sam Martin plans to retire in 2027, adding to the narrative of executive transition. The stock closed the session at $35.90 with a volume of 0.1 million shares, which is 0.1 times the 3-month average.

What The Data Shows

Celldex remains unprofitable with a trailing twelve-month (TTM) earnings per share (EPS) of -4.27 and TTM revenue down 88.6%. The stock has traded between $19.72 and $40.30 over the past 52 weeks. Despite recent positive clinical data from its Barzolvolimab and CDX-622 programs, the stock has underperformed in recent weeks, with sentiment trending lower, dropping from a 30-day average of 57/100 to 50/100 over the last seven days. The stock’s beta of 0.90 suggests it is slightly less volatile than the broader market.

What To Watch

Investors should continue to monitor Celldex’s leadership developments and any upcoming corporate actions. The company is scheduled to highlight further data from its clinical programs at the EAACI Annual Congress 2026, which may influence investor sentiment in the coming weeks.

AI-assisted analysis composed exclusively from headlines and data on the Top Tier newswire. Public view is delayed 4 hours from real time. Not financial advice.

CLDX by the numbers

Last: $32.81Session: -13.42%7 sessions: -8.08%Coverage: 9 stories / 8 sourcesAI sentiment: 58/100 (bullish)Mkt cap: $3.0B52w: $19.72 to $40.30
CLDX · today's session (5-min) · -12.38% vs prior close · updated 11:03 AM ET
$22.51$36.45$50.40prev close $37.89$33.207:00 AM8:00 AM9:00 AM10:00 AM11:00 AM7:00 AM · $48.907:05 AM · $45.007:10 AM · $40.007:15 AM · $40.007:20 AM · $39.827:25 AM · $37.257:30 AM · $35.757:35 AM · $35.387:40 AM · $34.507:45 AM · $34.697:50 AM · $34.507:55 AM · $34.008:00 AM · $29.008:05 AM · $24.008:10 AM · $27.358:15 AM · $26.458:20 AM · $26.508:25 AM · $30.048:30 AM · $29.678:35 AM · $32.508:40 AM · $31.118:45 AM · $33.508:50 AM · $34.508:55 AM · $34.539:00 AM · $35.209:05 AM · $35.549:10 AM · $35.599:15 AM · $36.399:20 AM · $37.009:25 AM · $36.609:30 AM · $37.709:35 AM · $37.369:40 AM · $38.019:45 AM · $36.489:50 AM · $36.849:55 AM · $35.9310:00 AM · $35.2310:05 AM · $35.3410:10 AM · $34.4510:15 AM · $33.9810:20 AM · $33.3710:25 AM · $32.4110:30 AM · $31.5510:35 AM · $31.6110:40 AM · $31.6410:45 AM · $32.5310:50 AM · $33.0010:55 AM · $33.2711:00 AM · $33.20
AI sentiment, last 36h · averaged over 9 stories · 58/100 bullish
AI sentiment 58/100 (bullish)0 · bearish50bullish · 100

The headlines behind the move

Story flow · 9 stories on the wire, last 36h · hover or tap a dot for the headline
36h ago24h ago12h agonowStockTitan · sentiment 76 · Celldex Announces Positive Results from Phase 3 EMBARQ-CSU1 and EMBARQ-CSU2 Studies of Barzolvolimab Which Met Primary and All Key Secondary EndpointsStockTitan · 76Celldex Announces Positive Results from Phase 3 EMBARQ-CSU1 and EMBARQ-CSU2 Studies of Ba…The Fly · sentiment 73 · Celldex’s barzolvolimab meets endpoints in Phase 3 urticaria trialThe Fly · 73Celldex’s barzolvolimab meets endpoints in Phase 3 urticaria trialSEC 8-K · sentiment 50 · Celldex Therapeutics, Inc. (CLDX) files 8-KSEC 8-K · 50Celldex Therapeutics, Inc. (CLDX) files 8-KInvesting.com Markets · sentiment 73 · Celldex stock rises after positive phase 3 trial resultsInvesting.com Markets · 73Celldex stock rises after positive phase 3 trial resultsMarketChameleon · sentiment 73 · Celldex reports Phase 3 barzolvolimab CSU wins as complete response rates approach 54% by Week 24MarketChameleon · 73Celldex reports Phase 3 barzolvolimab CSU wins as complete response rates approach 54% by…Investing.com Markets · sentiment 32 · Why is Celldex Therapeutics stock plummeting today?Investing.com Markets · 32Why is Celldex Therapeutics stock plummeting today?Seeking Alpha · sentiment 34 · Celldex falls after late-stage trial data for hives therapySeeking Alpha · 34Celldex falls after late-stage trial data for hives therapyInvestorsHub · sentiment 73 · Celldex Shares Rise 8% as Barzolvolimab Meets Primary Endpoints in Two Phase 3 TrialsInvestorsHub · 73Celldex Shares Rise 8% as Barzolvolimab Meets Primary Endpoints in Two Phase 3 TrialsReuters · sentiment 38 · Celldex shares slip as safety concerns cloud skin drug trial winReuters · 38Celldex shares slip as safety concerns cloud skin drug trial win
10m agoReutersBEARISH 38General

Celldex shares slip as safety concerns cloud skin drug trial win

1h agoInvestorsHubBULLISH 73Earnings

Celldex Shares Rise 8% as Barzolvolimab Meets Primary Endpoints in Two Phase 3 Trials

Celldex shares rise 8% as barzolvolimab meets primary and key secondary endpoints in two Phase 3 trials for chronic spontaneous urticaria.

2h agoSeeking AlphaBEARISH 34Product/PR

Celldex falls after late-stage trial data for hives therapy

Celldex (CLDX) stock sank after the company posted Phase 3 trial data for its hives therapy. Read more here.

3h agoInvesting.com MarketsBEARISH 32General

Why is Celldex Therapeutics stock plummeting today?

Why is Celldex Therapeutics stock plummeting today?

3h agoMarketChameleonBULLISH 73Product/PR

Celldex reports Phase 3 barzolvolimab CSU wins as complete response rates approach 54% by Week 24

Celldex reported positive topline Phase 3 results from EMBARQ-CSU1 and EMBARQ-CSU2, with barzolvolimab meeting the primary endpoint and all key secondary endpoints at Week 12. Complete response (UAS7=0) rates were significantly higher than placebo and climbed to as high as 54.00% by Week 24 in EMBARQ-CSU2, while benefits also extended to omalizumab-refractory patients and angioedema resolution. The trials continue to 52 weeks, and Celldex anticipates a BLA submission in 2027.

3h agoInvesting.com MarketsBULLISH 73Product/PR

Celldex stock rises after positive phase 3 trial results

Celldex stock rises after positive phase 3 trial results

4h agoSEC 8-KNEUTRAL 50General

Celldex Therapeutics, Inc. (CLDX) files 8-K

Filed: 2026-09-22 AccNo: 0001104659-26-109465 Size: 245 KB Item 8.01: Other Events Item 9.01: Financial Statements and Exhibits

4h agoThe FlyBULLISH 73Product/PR

Celldex’s barzolvolimab meets endpoints in Phase 3 urticaria trial

4h agoStockTitanBULLISH 76Product/PR

Celldex Announces Positive Results from Phase 3 EMBARQ-CSU1 and EMBARQ-CSU2 Studies of Barzolvolimab Which Met Primary and All Key Secondary Endpoints

Frequently asked questions

Why is CLDX stock down today?

CELLDEX THERAPEUTICS (CLDX) is down -13.42% in the latest session. Our newswire has captured 9 stories on CLDX across 8 sources in the last 36 hours, with AI sentiment reading bullish (avg 58/100). The most recent driver: "Celldex shares slip as safety concerns cloud skin drug trial win" (Reuters).

Is CLDX a buy right now?

Top Tier Newswire does not give financial advice. Our AI sentiment across the last 36 hours of CLDX coverage reads 58/100 over 9 stories; treat it as a research signal and do your own diligence.

How fast does this page update?

The data sections refresh continuously as the newswire lands coverage; the written analysis is published once per trading day. Pro subscribers additionally get real-time push alerts, watchlists, and the full live terminal.

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